2024-07-22 - Cancer Synoptic Reporting Project Group Meeting

Updates:

a. UICC

b. ICCR

1. UICC in process
2. ICCR in process

Implementation Guide Update

1. Ready to go with some minor updates

ICCR Terminology Bindings 

1. Will use NLM SDC/FHIR construct for content management and distribution

Manuscript update

1. Comments back by 6/15.

Clinical findings resolution

1.  How to encode the data "on the slide"?
2. Is this a series of independent observable entities that collectively tell the "story"?  (Similar to the intent of the synoptic?)

For example:

1. Gene/protein target of stain
2. Antibody used (and clone)
3. Cytoplasma?  Membraneous?  Nuclear?
4. Distribution

Need to define the building blocks (legos) of the data on the slide.  How the legos can be put together would need to be defined.  And how much detail do the legos need to be defined.

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PDL1 to start

1. Measuring - Positivity of presence of ant and semi-quantitative

2. How measuring

3. antibody used and clone

1. Maybe precoord not best for now.
2. Set of bound data points (observations?)
3. Try a couple of options/example

1. BN on Histology Quality overview
2. BN on Obs. ent vs. Clinical findings
   
   
3. Direct local extension BN.