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Overview

Creation of substance concepts that contain terms such as “free” (or "unbound" or "unconjugated") is limited to the measurement of biological substances (Observable entities, evaluation procedures, LOINC collaboration project) or to report their level (clinical findings). These concepts are created as siblings of the base concepts with a "substance X and X derivatives" or "X and X compound" as common supertype.

Modeling (stated view)

Parent concept

Most distal appropriate descendant of 105590001 |Substance (substance)|

Semantic tag

(substance)

Definition status

900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept)|

Attribute

726542003 |Has disposition (attribute)|

Naming Guidelines

FSN

Pattern: Free X (substance)

For example,

      • Free iodine (substance)

Preferred Term

Pattern: Free X

For example,

      • Free iodine

Synonyms

Optional pattern: Unbound x

For example,

      • Unbound iodine

Exemplar

The following illustrates both the stated and inferred view:


The following illustrates the hierarchy view:



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