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Overview

Groupers based on structural properties of the substance that are deemed to be clinically useful will be included in the Substance hierarchy.

Example:

  • Benzodiazepine (substance)
  • Quinolone (substance)

Modeling (stated view)

Parent concept

Most distal appropriate descendant of 312413002||Substance categorized by structure (substance)|

  • Exceptions: none identified
Semantic tag
  • (substance)
Definition status

900000000000074008|Necessary but not sufficient concept definition status (core metadata concept)

  • Exceptions: none identified

Attributes

None

  • Exceptions: none

Exemplar for Concept Model

The following illustrates the stated and inferred view.



Terming Guidelines


FSN

Use the following pattern for the FSN. Groupers should be expressed in the singular. (Compound not compounds)

Example for substances that represent a structural grouper:

  • Organic nitrogen compound (substance)
  • Halide compound (substance)

  • Triazine derivative (substance)
  • Copper and/or copper compound (substance)
  • Phenothiazine and/or phenothiazine derivative (substance)
  • Nucleotide (substance)

Where the same word is used to identify both a group of substances with a particular chemical structure and a particular chemical substance the following terming for the FSN will be used for the substance grouper concept.
Substance with X structure (substance)
Examples:

  • Substance with tetracycline structure (substance)

  • Substance with cresol structure (substance)
  • Substance with benzene structure (substance)

Preferred Term

Use the following pattern for the Preferred Term, 

Example:

  • Organic nitrogen compound
  • Halide compound

  • Triazine derivative
  • Copper and/or copper compound
  • Phenothiazine and/or phenothioazine derivative
  • Nucleotide

Where the same word is used to identify both a group of substances with a particular chemical structure and a particular chemical substance the following pattern will be used for PT the substance grouper concept.

Substance with X structure
Examples:

  • Substance with tetracycline structure

  • Substance with cresol structure
  • Substance with benzene structure

Synonyms

A synonym to match the FSN must be created.

Additional synonyms are not allowed unless explicitly identified as an exception in the Editorial Guidelines.

Exemplar for Hierarchy

Figure 1: Browser view of 299979007 |Organic nitrogen compound (substance)|




Figure 2: Browser view of 767209009 |Copper and/or copper compound (substance)|




Figure 3: Browser view of 766224008 |Substance with cresol structure (substance)|






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