SNOMED CT Editorial Guide

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Overview

The Medicinal Product "containing" (MP-containing) concept is an abstract representation of the active ingredient(s) for a medicinal product. It means that the medicinal product must contain the active ingredient(s) specified in the FSN but may also contain a modification of the active ingredient(s) specified in the FSN or may contain additional active ingredient(s).

For example,

    • Product containing axitinib (medicinal product)
    • Product containing abacavir and lamivudine (medicinal product) 

Modeling (stated view)

Stated parent concept

763158003 |Medicinal product (product)

Semantic tag(medicinal product)
Definition status900000000000073002 |Sufficiently defined by necessary conditions definition status (core metadata concept)|

Attribute:

Has active ingredient

Range: 105590001 |Substance (substance) - descendants only, excluding concepts representing structural groupers, dispositions, or combined substances

Cardinality: 1..* - there is no technical limit on the number of Has active ingredient attributes that may be added to a concept; a practical limit may be imposed at a later date.

For content in the International Release, this attribute value should represent the base ingredient, not a modification, unless explicitly identified as an exception.

  • Exceptions:
    • Chemical element with multiple modification (e.g. 422232005 |Calcium lactate gluconate (substance)|)
    • Chloral hydrate (e.g. 28748001 |Product containing chloral hydrate (medicinal product)|)
    • Liposome or lipid complex substances (e.g. 426490000 |Vincristine liposome (substance)|, 425953004 |Amphotericin B lipid complex (substance)|)
    • Pegylated substance (e.g. 385544005 |Pegfilgrastim (substance)|, 770965008 |Pegvaliase (substance)|)
    • Radiopharmaceutical (e.g. 783864004 |Product containing cyanocobalamin (58-Co) (medicinal product)|, 783854008 |Product containing sodium iodide (131-I) (medicinal product)|)
    • Silver sulfadiazine (e.g. 19630009 |Product containing silver sulfadiazine (medicinal product)|)
    • Benzylpenicillin (e.g. 323404007 |Product containing benzathine benzylpenicillin (medicinal product)|)

Naming Guidelines

FSN

Use the following pattern for the FSN; align naming and case sensitivity with the FSN for the concept that is selected as the attribute value, excluding the semantic tag. For multiple ingredient drug products, the active ingredients must be in alphabetical order and separated by the word “and”.

  • Product containing <Active ingredient FSN> (medicinal product)
  • Product containing <Active ingredient FSN> and <Active ingredient FSN> (medicinal product)
  • Product containing <Active ingredient FSN> and <Active ingredient FSN> and <Active ingredient FSN tag> (medicinal product)

For example,

      • Product containing axitinib (medicinal product)
      • Product containing abacavir and lamivudine (medicinal product)
      • Product containing abacavir and lamivudine and zidovudine (medicinal product)

Preferred Term

Use the following pattern for the PT; align naming and case sensitivity with the PT for the concept that is selected as the attribute value. For multiple ingredient drug products, the active ingredients must be in alphabetical order and separated by the word “and”.

  • <Active ingredient PT>-containing product
  • <Active ingredient PT>- and <Active ingredient PT>-containing product
  • <Active ingredient PT>- and <Active ingredient PT>- and <Active ingredient PT>-containing product

For example,

      • Axitinib-containing product
      • Abacavir- and lamivudine-containing product
      • Abacavir- and lamivudine- and zidovudine-containing product
Synonym

Synonyms matching the FSN are not required.

Exemplars

The following illustrates the stated view for 714627007 |Product containing aflibercept (medicinal product)|:

The following illustrates the inferred view for 714627007 |Product containing aflibercept (medicinal product)|:

The following illustrates the stated view for 412556009 |Product containing codeine and paracetamol (medicinal product)|:

The following illustrates the inferred view for 412556009 |Product containing codeine and paracetamol (medicinal product)|:


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