EDQM updates (Source) - July 2022 to September 2023
Inactivations in EDQM
| # | Code | Term | Status | DEUSG Action / Plan | |
|---|---|---|---|---|---|
| 1 | 13136000 | Gastro-resistant powder for oral suspension | Not Referenced | No action required | |
| ui2 | 10609000 | Eye drops, prolonged-release | Not Referenced | No action required | |
| 3 | 50056000 | Prolonged-release granules for oral suspension | Not Referenced | No action required | |
| 4 | 50026000 | Gastro-resistant granules for oral suspension | Not Referenced | No action required | |
| 5 | 10307000 | Oromucosal drops | Not Referenced | No action required | |
| 6 | 50036000 | Modified-release granules for oral suspension | Not Referenced | No action required | |
New codes in EDQM (1st review by the content Team)
# | Code | Term | Status | Content team evaluation | Products that use this form | Expert feedback | Action / Plan |
|---|---|---|---|---|---|---|---|
| 1 | 13179000 | Granules for modified-release oral suspension | Not Referenced | ||||
| 2 | 13184000 | Powder for solution for provocation test | Not Referenced | Not in scope | Julie M. James has too much specificity about the use, which is out of scope for SNOMED PDF | No action required | |
| 3 | 13168000 | Oromucosal drops, solution | Not Referenced | ||||
| 4 | 13169000 | Oromucosal drops, suspension | Not Referenced | ||||
| 5 | 13177000 | Granules for gastro-resistant oral suspension | Not Referenced | ||||
| 6 | 13165000 | Suspension for gel | Not Referenced | ||||
| 7 | 13178000 | Powder for gastro-resistant oral suspension | Not Referenced | ||||
| 8 | 13162000 | Concentrate for cutaneous emulsion | Not Referenced | ||||
| 9 | 13180000 | Granules for prolonged-release oral suspension | Not Referenced | ||||
| 10 | 13159000 | Eye drops, prolonged-release solution | Not Referenced | ||||
| 11 | 13175000 | Prolonged-release chewable tablet | Not Referenced | ||||
| 12 | 13176000 | Powder for prolonged-release oral suspension | Not Referenced | ||||
| 13 | 13167000 | Oromucosal drops, emulsion | Not Referenced |
SNOMED Updates (Target) - July 2022 to September 2023
Inactivations in SNOMED CT (Select map targets if available)
# | ConceptId | Term | Status | Action / Plan | Discussion |
|---|---|---|---|---|---|
| 1 | 840651000 | Conventional release chewable capsule (dose form) | Not Referenced | See https://request.ihtsdotools.org/#/requests/preview/766062?fromList=true request from François Macary Hi François, The existing Pharmaceutical dose form concept and the associated Clinical drug concept modeled using it have been inactivated and replaced because the requested changes for the Basic dose form would alter the meaning of the concepts. The addition of an additional Administration method will be addressed at a later date; it is a change that needs to be done systematically for all affected concepts and also requires additional testing and perhaps a concept model change. Kind regards, | |
| 2 | 421873001 | Conventional release oral cream (dose form) | Not Referenced | Looking in browser the inactivation target is 1217290000 |Conventional release oromucosal cream (dose form)|. Can see this was added based on a request from François Macary referencing EDQM PDF mapping; e-prescribe; e-dispense: https://request.ihtsdotools.org/#/requests/preview/767928?fromList=true | |
| 3 | 783749008 | Conventional release oral ointment (dose form) | Not Referenced | Inactivation target is 1217289009 |Conventional release oromucosal ointment (dose form)| that was added based on a request from François Macary referencing EDQM PDF mapping; e-prescribe; e-dispense: https://request.ihtsdotools.org/#/requests/preview/767927?fromList=true | |
| 4 | 1231841006 | Porous impregnated material for conventional release vapor inhalation (dose form) | Referenced | Pending | Mapped to EDQM: 50033100 Inhalation vapour, impregnated plug Historical associations to active concepts:
Christopher Jarvis Inhalation implies pulmonary, favors replacing by 1269278009 |Porous impregnated material for conventional release pulmonary vapor inhalation (dose form)| EDQM Interested in understanding the product with more detail. Ian Spiers The source materials defined that there was oromucosal use in nicotine cartridges. Original request from Sweden. https://www.medicines.org.uk/emc/product/4707/smpc#gref "Nicorette 15mg Inhalator: inhalation cartridge for oromucosal use" Nicola Ingram Request was from Ireland SPC http://www.hpra.ie/img/uploaded/swedocuments/Licence_PA0330-037-010_31072023145601.pdf page 3 "The patient may find deep drawing or short sucks on the mouthpiece most effective – patients soon find a favoured technique. Nicotine vapour passing through the mouth is absorbed by the buccal mucosa: little reaches the lungs." Problem was that 1231841006 |Porous impregnated material for conventional release vapor inhalation (dose form)| was pulmonary dose form. Inactivation reason for Porous impregnated material for conventional release vapor inhalation (dose form) may be incorrect (did not add corresponding clinical drug as failed release validation check). Julie M. James respiratory track does not include oromucosal. Guillermo Reynoso why is the inactivation reason Outdated? Maybe an option is to maintain the more general concept and add the new ones as children |
| 5 | 784575004 | Conventional release oral spray (dose form) | Not Referenced | Unsure why Toni inactivated but new concept requested by François Macary 1229934008 |Conventional release emulsion for oromucosal spray (dose form)| https://request.ihtsdotools.org/#/requests/preview/769485?fromList=true | |
| 6 | 784576003 | Prolonged-release intrauterine drug delivery system (dose form) | Not Referenced | https://request.ihtsdotools.org/#/requests/preview/769521?fromList=true request from François Macary Hi François, Due to the types of changes being requested, the existing concept will be inactivated and replaced with a new concept instead of being updated. Kind regards, |
New concepts in SNOMED CT (Candidates for creating new maps)
# | ConceptId | term | Status | Source | Action / Plan |
|---|---|---|---|---|---|
| 1 | 1237270004 | Concentrate for conventional release solution for peritoneal dialysis (dose form) | Not Referenced | Request from François Macary referencing EDQM (DEUSG, EDQM PDF mapping): https://request.ihtsdotools.org/#/requests/preview/770954?fromList=true | |
| 2 | 1287605002 | Conventional release solution for intraperitoneal instillation (dose form) | Not Referenced | https://request.ihtsdotools.org/#/requests/preview/776647?fromList=true https://www.hpra.ie/img/uploaded/swedocuments/Licence_PA22637-005-001_12062019164057.pdf | |
| 3 | 1231815000 | Conventional release oral or pulmonary solution (dose form) | Not Referenced | Request from François Macary referencing EDQM (DEUSG, EDQM PDF mapping): https://request.ihtsdotools.org/#/requests/preview/764561?fromList=true | |
| 4 | 1237318003 | Concentrate for conventional release emulsion for cutaneous spray (dose form) | Referenced | No action required | |
| 5 | 1255299001 | Tablet for conventional release oromucosal solution for mouthwash (dose form) | Referenced | No action required | |
| 6 | 1237310005 | Concentrate for conventional release oromucosal solution for gargle (dose form) | Referenced | No action required | |
| 7 | 1255234008 | Conventional release suspension for infusion and/or injection (dose form) | Not Referenced | Probably added by Toni as part of project adding 'infusion and/or injection' groupers. | |
| 8 | 1237287002 | Concentrate for conventional release cutaneous solution (dose form) | Referenced | No action required | |
| 9 | 1237289004 | Concentrate for conventional release oromucosal solution (dose form) | Referenced | No action required | |
| 10 | 1231816004 | Conventional release intravesical or parenteral or urethral solution (dose form) | Not Referenced | Request from François Macary referencing EDQM (DEUSG, EDQM PDF mapping): https://request.ihtsdotools.org/#/requests/preview/764560?fromList=true | |
| 11 | 1237073006 | Prolonged-release intrauterine delivery system (dose form) | Referenced | No action required | |
| 12 | 1237274008 | Concentrate for conventional release dispersion for infusion and/or injection (dose form) | Not Referenced | Probably added by Toni as part of project adding 'infusion and/or injection' groupers. | |
| 13 | 1237285005 | Concentrate for conventional release emulsion for infusion and/or injection (dose form) | Not Referenced | Probably added by Toni as part of project adding 'infusion and/or injection' groupers. | |
| 14 | 1237267003 | Concentrate for conventional release solution for infusion (dose form) | Referenced | No action required | |
| 15 | 1237263004 | Concentrate for conventional release suspension for injection (dose form) | Referenced | No action required | |
| 16 | 1237288007 | Concentrate for conventional release intravesical solution (dose form) | Referenced | No action required | |
| 17 | 1237264005 | Concentrate for conventional release oral suspension (dose form) | Referenced | No action required | |
| 18 | 1269279001 | Porous impregnated material for conventional release oromucosal vapor inhalation (dose form) | Not Referenced | See above SNOMED updates | |
| 19 | 1237284009 | Concentrate for conventional release emulsion for infusion (dose form) | Referenced | No action required | |
| 20 | 1237266007 | Concentrate for conventional release rectal solution (dose form) | Not Referenced | Request from François Macary referencing EDQM: https://request.ihtsdotools.org/#/requests/preview/770948?fromList=true | |
| 21 | 1237271000 | Concentrate for conventional release dispersion for injection (dose form) | Referenced | No action required | |
| 22 | 1237293005 | Concentrate for conventional release solution for nebulizer (dose form) | Referenced | No action required | |
| 23 | 1237265006 | Concentrate for conventional release oral solution (dose form) | Referenced | No action required | |
| 24 | 1255346009 | Conventional release intestinal gel (dose form) | Referenced | No action required | |
| 25 | 1237273002 | Concentrate for conventional release dispersion for infusion (dose form) | Referenced | No action required | |
| 26 | 1237286006 | Concentrate for conventional release emulsion for injection (dose form) | Referenced | No action required | |
| 27 | 1237291007 | Concentrate for conventional release solution for intraocular irrigation (dose form) | Referenced | No action required | |
| 28 | 1269278009 | Porous impregnated material for conventional release pulmonary vapor inhalation (dose form) | Not Referenced | See above SNOMED updates | |
| 29 | 1237269000 | Concentrate for conventional release solution for infusion and/or injection (dose form) | Not Referenced | Probably added by Toni as part of project adding 'infusion and/or injection' groupers. | |
| 30 | 1255237001 | Lyophilized powder for conventional release solution for infusion and/or injection (dose form) | Not Referenced | Original lyophilized dose form request: https://request.ihtsdotools.org/#/requests/preview/725602?fromList=true probably added by Toni as part of project adding infusion and/or injection groupers. | |
| 31 | 1237290008 | Concentrate for conventional release oral or rectal solution (dose form) | Referenced | No action required | |
| 32 | 1237275009 | Concentrate for conventional release solution for hemodialysis (dose form) | Referenced | No action required | |
| 33 | 1237268008 | Concentrate for conventional release solution for injection (dose form) | Referenced | No action required | |
| 34 | 1255338008 | Conventional release chewable soft capsule (dose form) | Referenced | No action required | |
| 35 | 1279737007 | Prolonged-release solution for eye drops (dose form) | Not Referenced | Request from Alejandro referencing EDQM map: https://request.ihtsdotools.org/#/requests/preview/776391?fromList=true | |
| 36 | 1255347000 | Intestinal dose form (dose form) | Not Referenced | Added in 2022 has one descendant 1255346009 |Conventional release intestinal gel (dose form)| that is a request from Request from François Macary referencing EDQM (DEUSG, EDQM PDF mapping and 2022-06-20 EDQM to SNOMED Dose Form Map call) https://request.ihtsdotools.org/#/requests/preview/770417?fromList=true | |
| 37 | 1231817008 | Powder for conventional release intravesical or parenteral or urethral solution (dose form) | Not Referenced | Request from François Macary referencing EDQM PDF: https://request.ihtsdotools.org/#/requests/preview/764559?fromList=true |