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Date 22nd January 2025

GoToMeeting Details

Zoom link - https://snomed.zoom.us/my/pathologycrg 

Recording 

https://snomed.zoom.us/rec/share/T8pefG3dZCq9IBYp6ERXqkiIIqLvtgidqoKKtVodxPoIV04Zbx7AFtDZFJM9PwDC.UCwg6xc7Scq9dUjY

Passcode: 0^D^sEk% 

Discussion items

ItemDescriptionOwnerNotesAction
1

Review actions log and issues and decisions log

All


2UK concept promotion request from Netherlands

KN / Feikje Hielkema-Raadsveld


Dutch software vendor whose software connects to that of Abbott. They are receiving SNOMED codes from the UK extension

  • "coding" : {
  • "system" : http://snomed.info/sct,

      • "code" : "1464671000000104",
      • "display" : "Mean substance concentration of glucose in capillary blood using minimally-invasive continuous glucose monitoring device (observable entity))"
      • "
      coding" : {
      • "system" : http://snomed.info/sct,
      • "code" : "1464761000000101",
      • "display" : "Coefficient of variation of mean substance concentration of glucose in capillary blood using minimally-invasive continuous glucose monitoring device (observable entity) "
    • "coding" : {
      • "code" : "1464781000000105",
      • "display" : "Percentage of time in target glucose range to total glucose monitoring time using minimally-invasive continuous glucose monitoring device (observable entity) "
    • "coding" : {
      • "code" : "1464931000000109",
      • "display" : "Mean number of self-monitored capillary blood glucose measurements per day (observable entity)"
      "coding
      • "
      : {
      • "system" : http://snomed.info/sct,
      • "code" : "1464911000000101",
      • “display" : "Number of clinically significant hypoglycaemic episodes recorded by continuous glucose monitoring device (observable entity)"
      "coding
      • "
      : {
      • "system" : "http://snomed.info/sct","code" : "1464941000000100",
      • "display" : "Percentage of successful data capture time to total expected continuous glucose monitoring sensor wear time using minimally-invasive continuous glucose monitoring device (observable entity)"
      • "
      coding" : {
      • "system" : "http://snomed.info/sct",
      • "code" : "1464891000000104",
      • "display" : "Glucose Management Indicator expressed as substance concentration ratio (observable entity))"
    • "coding" : {
      • "code" : "1464891000000104",
      • "display" : "Glucose Management Indicator expressed as substance concentration ratio (observable entity))"
      "coding
      • "
      : {
      • "system" : "http://snomed.info/sct",
      • “code" : "1464831000000100",
      • "display" : "Percentage of time below level 1 hypoglycaemic threshold to total continuous glucose monitoring time using minimally-invasive continuous glucose monitoring device (observable entity)"
      "coding
      • "
      : {
      • "system" : "http://snomed.info/sct","code" : "1464821000000102",
      • "display" : "Percentage of time below level 2 hypoglycaemic threshold to total continuous glucose monitoring time using minimally-invasive continuous glucose monitoring device (observable entity)"
      "coding
      • "
      : {
      • "system" : "http://snomed.info/sct",
      • "code" : "1464801000000106",
      • "display" : "Percentage of time above level 1 hyperglycaemic threshold to total continuous glucose monitoring time using minimally-invasive continuous glucose monitoring device (observable entity) "
      "coding
      • "
      : {
      • "
      • system" : "http://snomed.info/sct","code" : "1464791000000107",
      • "display" : "Percentage of time above level 2 hyperglycaemic threshold to total continuous glucose monitoring time using minimally-invasive continuous glucose monitoring device (observable entity)"

    Stan and Pam to take to LOINC-SI group to discuss options to make the codes available internationally 

    3

    Qualitative and semi-quantitative representation in SNOMED CT

    KN


    Carried over to next session

    4




     AOB



    Actions log

    ItemDescriptionOwnerNotesAction
    1

    April 2025 business meeting session for this group

    KN / JC

    Face-to-face session would be beneficial to tackle some primary issues

    Meeting slot has been allocated for Tuesday 8th April 9-12.30 CET

    Jim Campbell to chair

    Karim to co-chair

    2

    UK need to consider whether inheres_in is superfluous in lab result reporting and align with international terminology

    KN / APWe agree it does not add anything but need to add to internal UK NRC log for discussion

    On hold

    3

    Time aspect modelling

    KN / AP

    modelling single point in time explicitly to enable correct classification of content

    Internal UK NRC log for discussion

    Daniel to give a short presentation on time aspect - needs further discussion

    On hold

    Discussed with lab experts and the requirement is the same as the LOINC Ontology - time-specific concepts must not be subsumed by unmodelled soft default implicit 'single point in time' concepts

    4SARS-Cov2 observable entity concepts for reporting viral RNA presence in the SNOMED CT International EditionFA

    These concepts are modelled with both inheres_in and direct_site

    Farzaneh to take these back and discuss internally for a steer on the use of inheres_in for these concepts

    On hold

    SI propose to remove inheres_in but await formal decision from this group

    5Use of inheres_in for 

    colour, appearance, identification

    FAinheres_in  used for the property to describe the characteristic of an organism, cell or body structure - applicable to LOINC Ontology representationsFarzaneh to present
    6Fractions and ratiosAll IFCC-IUPAC Silverbook https://iupac.org/what-we-do/books/silverbook/ but also on the homepage: https://labterminology.com/list-of-kinds-of-property/

    Proposed to revisit after reviewing the resources


    7

    Relative concentration of a substance in two different specimens

    Relative concentration two different measurement properties

    KN / DK

    How do we assess effort vs impact? The requirement to model them accurately for machine reasoning - auto-classifications; erroneous subsumptions

    Karim reviewed the modelling options with Daniel and presented to group

    Relative_conc_modelling options.pptx

    Young Bae recommended we look at IUPAC relative properties and ratios

    What is the advantage in developing the full mathematical model in SNOMED CT? Limitations to what can be achieved

    General consensus that we should pursue via MAG

    Stan to take to LOINC-SI groupNeeds input from the LOINC Ontology plan - what is the intention for making these machine-readable?

















    Issues and decisions log

    ItemDescriptionOwnerNotesDecision 
    1Time aspect specification in description AND modellingAllConcept is primitive if the description is more specific than the modelling. Concept logical definition must not be more specific than concept description

    Must be stated consistently  in description AND modelling in accordance with SI editorial policy

    2Inheres_in is superfluous in lab result reportingAll

    Inheres_in effectively duplicates direct_site. They are two different perspectives (lab and clinical) of the same target

    Direct_site is suitable for sample-based diagnostics and not other areas but NPU will not be following those guidlines

    Direct_site attribute sufficiently captures specimen and derivable substance / site from specimen modelling 

    LOINC Ontology to model direct_site

    NPU to model inheres_in

    Create interoperable rules and document in guidance 

    Flagged for further discussion

    What about the requirement to classify extensions?

    3

    Representation of percent

    All

    Concept is primitive if the description is more specific than the modelling. Concept logical definition must not be more specific than concept description


    unit not required field in LOINC so in SNOMED CT, if fully defined without unit, could generate logical equivalences 

    Represent percent in the description and the unit in SNOMED CT in accordance with SI editorial policy - provisional decision?

    LOINC Committee decided to remove 100 denominator and reflect percent as UoM - SNOMED CT modelling still under investigation

    Needs update from Stan


    4

    Inconsistencies - International content for cancer synoptic reporting by immunohistochemistry

    1255078008 | Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm by immunohistochemistry (observable entity) |

    All

    Does not use percent unit in modelling

    e.g. 1 - modelling time_aspect -> single point in time but not stating this in the description

    In contrast to LOINC Ontology examples that do state 'at single point in time' in the description and model in the logic

    e.g.2 - use inheres_in whereas LOINC Ontology used direct_site

    SI are adding percent unit to the content

    Awaiting formal decision on inheres_in from this group

    Awaiting formal decision on time_aspect from this group

    5



















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