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Salts should be modeled with a conjugate base as parent (if one exists, otherwise they are modeled with a structural parent). Salts may have an Is modification of (attribute) relationship to the conjugate acid where a specific use case is identified. See examples of such use cases in the "Concepts Representing a Substance or its Modifications" section page of this Editorial Guide.
Conjugate base concepts ( e.g. valproate, pamidronate, etidronate) should only be created where a specific use case is identified, for example, when required to support the definition of other concepts in the terminology.
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New instances of substance concepts containing the word "salt" will not be added. The existing concepts will be reviewed, and if possible, will be replaced by equivalent compounds.
Modeling
| Parent concept | Most distal appropriate descendant of 312413002 |Substance categorized structurally (substance)| |
|---|---|
| Semantic tag | (substance) |
| Definition status |
Primitive |
Attribute: |
|---|
Is Modification of | Range <105590001 |Substance (substance)| Cardinality: 0..1 Used to identify the conjugate acid |
|---|---|
Attribute: Has disposition | Range: <726711005 |Disposition (disposition)| |
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Cardinality: 0..1 |
Naming
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Where INN names exist, these should be used for the FSN and PT.
FSN | Pattern:
For example,
Exception:
|
|---|---|
Preferred Term | Pattern:
Exception:
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Synonyms | Pattern: Pamidronate X For example,
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Exemplar
The following illustrates the stated and inferred views.
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| Caption label | ||||
|---|---|---|---|---|
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Stated view of 387080000 |Valproic acid (substance)| |
| Caption label | ||||
|---|---|---|---|---|
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Stated and inferred view of 387481005 |Sodium valproate (substance)| |
| Caption label | ||||
|---|---|---|---|---|
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Hierarchy view of 264325000 |Valproate (substance)| subtypes |
The following illustrates the stated and inferred views.
Overview
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