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Groupers based on disposition that are deemed to be clinically useful and that can be sufficiently defined will be included in the |Substance| hierarchy. Disposition is defined as a behavior that a substance will exhibit or participate in, given the appropriate context. There is no requirement to introduce a new semantic tag in order to distinguish concepts representing a substance disposition from any other type of concept in the |Substance| hierarchy.
Note: This section applies to concepts representing a single disposition. It does not apply to concepts representing a disposition combined with a structural grouper or concepts representing more than one disposition.
Modeling
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Parent concept | 105590001 |Substance (substance)|
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Definition status |
Defined | |
|Has disposition| | Range: <726711005 |Disposition (disposition) |
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Cardinality: 1..1 |
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Note: Substance groupers representing etiopathic dispositions (e.g. 88376000 |Carcinogen (substance), 45986006 |Teratogen (substance)) will be created. Since most substances can exhibit these characteristics in some circumstances, the descendant concepts will not be populated. Exceptions will be noted in the editorial guidelines.
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The following illustrates the inferred view for grouper concepts based on disposition.
Terming
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FSN | Use the following pattern for the FSN. The FSN must reflect the terming used to describe the disposition consistent with the terming of the |Has disposition| attribute value. Example for dispositions that represent a mechanism of action:
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Preferred Term | Use the following pattern for the Preferred Term. The Preferred Term must reflect the terming used to describe the disposition consistent with the terming of the |Has disposition| attribute value. Example for dispositions that represent a mechanism of action:
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Synonyms | Synonyms corresponding to the FSN are not required. Additional synonyms are allowed only if they are consistent with the synonyms for the corresponding disposition concept. |
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