Overview
Groupers based on disposition that are deemed to be clinically useful and that can be sufficiently defined will be included in the |Substance| hierarchy. Disposition is defined as a behavior that a substance will exhibit or participate in, given the appropriate context. There is no requirement to introduce a new semantic tag in order to distinguish concepts representing a substance disposition from any other type of concept in the |Substance| hierarchy.
Note: This section applies to concepts representing a single disposition. It does not apply to concepts representing a disposition combined with a structural grouper or concepts representing more than one disposition.
Modeling
Parent concept | 105590001 |Substance (substance)|
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Definition status | Defined |
|Has disposition| | Range: <726711005 |Disposition (disposition)
Cardinality: 1..1
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Substance groupers representing etiopathic dispositions (e.g. 88376000 |Carcinogen (substance), 45986006 |Teratogen (substance)) will be created. Since most substances can exhibit these characteristics in some circumstances, the descendant concepts will not be populated. Exceptions will be noted in the editorial guidelines.
Exemplar for Grouper Concept Based on Disposition
The following illustrates the stated view for grouper concepts based on disposition.
The following illustrates the inferred view for grouper concepts based on disposition.
Terming
FSN | Use the following pattern for the FSN. The FSN must reflect the terming used to describe the disposition consistent with the terming of the |Has disposition| attribute value. Example for dispositions that represent a mechanism of action:
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Preferred Term | Use the following pattern for the Preferred Term. The Preferred Term must reflect the terming used to describe the disposition consistent with the terming of the |Has disposition| attribute value. Example for dispositions that represent a mechanism of action:
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Synonyms | Synonyms corresponding to the FSN are not required. Additional synonyms are allowed only if they are consistent with the synonyms for the corresponding disposition concept. |
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