Cancer Synoptic Reporting Project Group

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Cancer Synoptic Reporting Project Group

12 April 2022 at 14:00 - 16:30 UTC

Attendees 

Scott Campbell Suzanne Santamaria Elaine Wooler Raj Dash Stefan Dubois Laszlo Igali Paul Seegers Jim Case Anna Rossander Anita Flynn Sharon Sebastian Nick Booth

Thomas Ruediger Nicola Ingram

Zoom - https://snomed.zoom.us/my/pathologycrg


Meeting Recording (GoogleDrive)

https://drive.google.com/file/d/1iTFcIC9iwR_Ur-4i8lTHvous_8QC-bZT/view?usp=sharing

Discussion items

ItemDescriptionOwnerNotesAction
1

Tumor deposits

(Review)

Scott Campbell
  1. Colon/appendix (easier)
  2. Melanoma (satellites) (harder)
  1. Colon - This model holds for colon.  Some discussion of the use of characterizes = metastatic  discontinuous spread, but general agreement reached that this term both suffices and is accurate.

2. Melanoma (microsatellite) - Definition needs to stay primitive as definition of discontinuous spread from one part of the skin to another part of the skin structure AND within 2 cm cannot be modelled with necessary and sufficient conditions

diagram-1178984009.png

Possible to have process to extend to lymphatic vessel structure of skin.  Suggest hierarchy of concepts.  In-transit melanoma to be primitive for now.  Potential to include concrete domains to define such characteristics but must be discussed further.

2Tumor bud (Review)

Scott Campbell

Will leave as primitive....no way to model "cluster of cells at leading edge of invasive component of neoplasm"

  1. Presence of tumor buds - growth process << budding  

    Process could be defined as "budding" and included in the proliferation process qualifiers.  Then this could be considered sufficiently defined.  For now, concept will be left primitive
  2. diagram-1217526001.png


  3. Number of tumor buds.  This concept must be left primitive for now as there is no way to describe a tumor bud which consists of 1-4 cells at the leading edge of the invasive neoplasm.  
    diagram-1217527005.png


Agreed.


3PatternsScott Campbell
  1. How to handle patterns within histologies
    1. Lung (Lepidic, acinar)
    2. DCIS
    3. Bladder (differentiation)

Discussion surrounding morphologies and additional descriptors.

Histologies are authoritative based on pathologist interpretation.   Morphologic descriptors are subsequent phenotypic characteristics of the primary histology. Consider using qualifier values for growth patterns in protocols where required as supplemental/additional information to the actual histology

4Treatment effectScott Campbell

Continue discussion:

What are we measuring when assessing "treatment effect"?  

Is this a histologic change?  Viability of tumor cells?

  1. Primary site
  2. Lymph node

image2022-2-7_8-58-39.png

image2022-2-7_8-57-30.png


Not discussed.

5Lung tumor focality; synchronous Scott Campbell
  1. Focal, non-focal (multiple)
  2. Local metastases - sidedness? 
  3. count of local metastases

Group suggests that we take the approach of soliciting location of nodules by lobe, and then the logic of the forms and/or sidedness can be stated and/or calculated.

6Implementation workshop

Scott Campbell

Discuss interest in a session on implementation and useStrong agreement.  Paul Seegers, Stefan Dubois, Jim Campbell, Raj Dash, Laszlo Iglali all willing to be co-faculty 
7Histology taxonomy

Scott Campbell

Interest in revisiting with pathologistsStrong interest here and supported by SNOMED Intl.  Must coordinate work with Nikki Ingram's work.
8Additional work items as time allows

Scott Campbell


N/A


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