2022-04-12 - Cancer Synoptic Reporting Project Group Meeting Virtual Business Meeting

Tumor deposits

(Review)

1. Colon/appendix (easier)
2. Melanoma (satellites) (harder)

Possible to have process to extend to lymphatic vessel structure of skin.  Suggest hierarchy of concepts.  In-transit melanoma to be primitive for now.  Potential to include concrete domains to define such characteristics but must be discussed further.

Will leave as primitive....no way to model "cluster of cells at leading edge of invasive component of neoplasm"

Agreed.

1. How to handle patterns within histologies
   1. Lung (Lepidic, acinar)
   2. DCIS
   3. Bladder (differentiation)

Discussion surrounding morphologies and additional descriptors.

Histologies are authoritative based on pathologist interpretation.   Morphologic descriptors are subsequent phenotypic characteristics of the primary histology. Consider using qualifier values for growth patterns in protocols where required as supplemental/additional information to the actual histology

Continue discussion:

What are we measuring when assessing "treatment effect"?  

Is this a histologic change?  Viability of tumor cells?

1. Primary site
2. Lymph node

image2022-2-7_8-58-39.png

image2022-2-7_8-57-30.png

Not discussed.

1. Focal, non-focal (multiple)
2. Local metastases - sidedness? 
3. count of local metastases

Group suggests that we take the approach of soliciting location of nodules by lobe, and then the logic of the forms and/or sidedness can be stated and/or calculated.