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07-22-2024 at 16:30 - 17:30 UTC


Jim Case Elaine Wooler @rous @ross simpson

@jim mcnulty @birdsong Jieun Hwang Thomas Ruediger Scott Campbell 



Meeting Recording (GoogleDrive)


Discussion items

ItemDescriptionOwnerNotesAction
1

Updates:

a. UICC

b. ICCR


  1. UICC in process
  2. ICCR in process
2

Implementation Guide Update

  1. Ready to go with some minor updates

3

ICCR Terminology Bindings 

  1. Will use NLM SDC/FHIR construct for content management and distribution


4

Manuscript update

  1. Comments back by 6/15.


5

Clinical findings resolution

Scott Campbell reviewing with editors


6Immunostains

Discussion on how to proceed

  1.  How to encode the data "on the slide"?
  2. Is this a series of independent observable entities that collectively tell the "story"?  (Similar to the intent of the synoptic?)

For example:

  1. Gene/protein target of stain
  2. Antibody used (and clone)
  3. Cytoplasma?  Membraneous?  Nuclear?
  4. Distribution


Need to define the building blocks (legos) of the data on the slide.  How the legos can be put together would need to be defined.  And how much detail do the legos need to be defined.

-------------

PDL1 to start

  1. Measuring - Positivity of presence of ant and semi-quantitative

2. How measuring

3. antibody used and clone



  1. Maybe precoord not best for now.
  2. Set of bound data points (observations?)
  3. Try a couple of options/example





1 hour


  1. BN on Histology Quality overview
  2. BN on Obs. ent vs. Clinical findings

  3. Direct local extension BN.  


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