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A recombinant (A new entity e.g., gene, protein, cell, or individual that results from genetic recombination) or synthetic/semi-synthetic substance (of, relating to, or produced by chemical or biochemical synthesis; especially: produced artificially) is similar in structure (but not identical to the naturally occurring substance). It should be created as a sibling of the naturally occurring substance.
A substance that is part of (e.g. dander) or is derived from (e.g. Insulin) an organism (human or non-human) is identical and should be created as a child of the naturally occurring substance.

Modeling

Parent concept	Most distal appropriate descendant of 105590001 \|Substance (substance)\|
Semantic tag	(substance)
Definition status	900000000000074008 \|Necessary but not sufficient concept definition status (core metadata concept)\|

Attribute

738774007 |

Is

Is modification of (attribute)| as applicable

726542003 |Has disposition (attribute)| as appropriate

“Recombinant”, “Synthetic”, or “Semi-synthetic” should precede the name of the substance

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FSN	Pattern: [Source organism] X (substance) Recombinant X (substance) Synthetic X (substance)

Example:

For example,

- - Human antithrombin III (substance)
  - Recombinant thrombin (substance)
  - Synthetic steroid (substance)

Preferred Term

Pattern:

Example:

For example,

Synonyms

Pattern: none identified

Example:


Exception	The naming of DNA, RNA, rRNA, antibody, Immunoglobulin, and antigen of organisms should follow the specific guideline for this type of substances.

Exemplar

Stated view of 411973001 |Bovine thrombin (substance)|

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