Descriptions:
| Term | description type | Language/acceptability | LangaugeLanguage/acceptability | Case significance |
|---|
Adverse [finding site] reaction to [agent] (disorder) | FSN | us:P | gb:P | ci |
Adverse [finding site] reaction to [agent] | SYN | us:P | gb:P | ci |
Concept model:
| Attribute Cardinality | Attribute | Value | Role group cardinality |
|---|
| 1..1 |
| Scg expression |
|---|
116680003|Is a (attribute)| |
|
| Scg expression |
|---|
281647001 |Adverse reaction (disorder)| |
| N/A |
| 1..1 |
| Scg expression |
|---|
246075003|Causative agent (attribute)| |
|
| Scg expression |
|---|
[agent] << 105590001|Substance (substance)| OR << 373873005|Pharmaceutical / biologic product (product)| |
| 1..1 |
| 0..1 |
| Scg expression |
|---|
363698007 |Finding site (attribute)| |
|
| Scg expression |
|---|
[finding site] <123037004 |Body structure (body structure)| |
|
Definition status:
| Scg expression |
|---|
900000000000073002|Defined (core metadata concept)| |
Template Language
281647001 |Adverse reaction (disorder)|: [[~1..1]] { [[~0..1]] 363698007 |Finding site (attribute)| = [[+id(< 123037004 |Body structure (body structure)|) @site]], [[~1..1]] 246075003 |Causative agent (attribute)| = [[+id( << 105590001 |Substance (substance)| OR << 373873005 |Pharmaceutical / biologic product (product)| OR << 260787004 |Physical object (physical object)| OR << 78621006 |Physical force (physical force)|) @agent]] }
Applies to:
| Scg expression |
|---|
<< 282100009 |Adverse reaction caused by substance (disorder)| MINUS <<418634005 |Allergic reaction caused by substance (disorder)| |
Editorial guidelines for selection of Causative agent attribute value:
The following editorial guidelines apply to concepts in the International Release; editorial guidelines for concepts in national extensions may vary.
...
- Groupers based on more than one role (e.g. 292722006 |Chelating agents and antidotes adverse reaction (disorder)|)
- Groupers based on body system or intended site or route of administration (e.g. 292548001 |Drug groups primarily affecting respiratory system adverse reaction (disorder)|) or 417895009 |Topical agent adverse reaction (disorder)|)
- Groupers based on disposition, role, or structure combined with an individual substance (e.g. 287177000 |Sulfonamide/trimethoprim reaction (disorder)| or 292513008 |Methyldopa and diuretic adverse reaction (disorder)|)
- Groupers based on "combined" or "compound" substances (e.g. 292983008 |Combined penicillin preparation adverse reaction (disorder)| or 293358005 |Compound iron preparations adverse reaction (disorder)|)
- Groupers based on disposition or structure combined with intended site or route of administration (e.g. 433494006 |Adverse effect of oral diphosphonate (disorder)|)
- Groupers based on disposition combined with role (e.g. 292265006 |Dopaminergic drug used in parkinsonism adverse reaction (disorder)|)
Rules for description generation:
- For the FSN, align terming and case sensitivity with the FSN for the concept that is selected as the attribute value, excluding the semantic tag.
- For the PT, align terming and case sensitivity with the US and GB PT for the concept that is selected as the attribute value.
- In cases where neither the US or GB PT matches the FSN, excluding the semantic tag, a synonym corresponding to the FSN is required unless explicitly identified as an exception.
- Additional synonyms "[agent] adverse reaction" should be added. Other synonyms are not allowed unless explicitly identified as an exception.
JIRA ticket for implementation: