...
Editorial guidelines for selection of Causative agent attribute value:
The following editorial guidelines apply to concepts in the International Release; editorial guidelines for concepts in national extensions may vary.
Hierarchy | Concept type | Allowed | Exception | Examples and Notes (Note: Examples are existing concepts and may not reflect the terming patterns described in the template.) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Substance | Base | yes | none | Adverse reaction concepts representing a substance base should preferentially be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example:
Expected classification (Agreed 21-Jan-2020):
| |||||||||||
Substance | Modification | no | yes | Adverse reaction concepts representing a substance modification should preferentially be modeled using a Causative agent that represents a substance base and is a descendant of 105590001 |Substance (substance)|. Concepts representing substance modifications are exceptions and could be included if they meeting the following criteria. Exceptions: NEED TO ADD CRITERIA Example: 292389002 |Fluphenazine decanoate adverse reaction (disorder)| Expected classification (Agreed 21-Jan-2020):
| |||||||||||
Substance | Disposition grouper | yes | none | Adverse reaction concepts representing a disposition grouper should preferentially be modeled using a Causative agent that is a descendant of 373873005 |Pharmaceutical / biologic product (product)|. In cases where that is not possible, then a concept from the 105590001 |Substance (substance)| may be used. Example:
Expected classification results (Agreed 21-Jan-2020):
| |||||||||||
ProductSubstanceDisposition | Role grouper | no | none | Adverse reaction concepts representing a role grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Note that role groupers will be transitioned to the 763158003 |Medicinal product (product)| hierarchy in future release. Example:
Expected classification results | Substance | Role grouper | no | none | Role groupers in the Substance hierarchy will be inactivated in a future release and should not be used for modeling in this subhierarchy. (Agreed 21-Jan-2020) Insert examples of role grouper. | Product | Role grouper | yes | none | Example: Expected classification results: TBD if there are any restrictions on which product roles can be used in modeling in this subhierarchy
| |
Product | Role + Structure grouper | no | TBD | No use case has been identified for use of this concept type for modeling in this subhierarchy. Existing groupers groupers representing role + structure will be inactivated and replaced with structure grouper. (Agreed 11-Feb-2020) Example:
| |||||||||||
Substance | Structure grouper | yes | none | Adverse reaction concepts representing a structure grouper should be modeled using a Causative agent that is a descendant of 105590001 |Substance (substance)|. Example:
Expected classification (Agreed 21-Jan-2020):
| |||||||||||
Product | Structure grouper | no | none | No use case has been identified for use of this concept type for modeling in this subhierarchy. Structure groupers in the Product hierarchy should only exist as SD concepts with a corresponding concept in the Substance hierarchy; the corresponding concept in the Substance hierarchy should be used for modeling in this subhierarchy. (Agreed 21-Jan-2020) | Product or Substance | Body system grouper | no | none | Body system groupers in both the Substance and Product hierarchies will be inactivated in a future release and should no longer be used for modeling in this hierarchy. (Agreed 21-Jan-2020) Example:
| ||||||
Product | Medicinal product-containing | yes | none | Example:
Expected classification results: Needs input from Drugs WG - see DRUGS-865
| |||||||||||
Product | Medicinal product-only | no | none | No use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product -containing concepts can be used for modeling in this subhierarchy. (Agreed 21-Jan-2020) | Product | Medicinal product form-containing | yes | none | Example:
Expected classification results: Needs input from Drugs WG - see DRUGS-866
| ||||||
Product | Medicinal product form-only | no | none | No use case has been identified for use of this concept type for modeling in this subhierarchy. Medicinal product form-containing concepts can be used for modeling in this subhierarchy. (Agreed 21-Jan-2020) | |||||||||||
Product | Clinical drug | no | none | No use case has been identified for use of this concept type for modeling in this subhierarchy. Extension model may provide sufficient use case for this. |
Rules for description generation:
...