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1.1. Post-coordination tools and resources

The expressions have been authored using the following resources and validated against the April 2024 Release of SNOMED International;

1.2. Examples of post-coordination

Below are examples of the common types of expressions generated. Whilst the process is essentially manual, by using a structured and repeatable approach, expressions can be produced which pass validation and are consistent and clinically valid. The  supporting resources indicated above should be used but combined with a wide knowledge of the topic.



HPO term example

SNOMED Expression - example

Approx.%

1

HP:0001525 Severe failure to thrive

54840006 |Failure to thrive (disorder)|:

{246112005 |Severity (attribute)|=24484000 |Severe (severity modifier) (qualifier value)|}

45%

2

HP:0004363 Abnormal circulating calcium concentration.

1217344005 |Finding of blood substance level (finding)|:

{363713009 |Has interpretation (attribute)| =394844007 |Outside reference range (qualifier value)|,

363714003 |Interprets (attribute)| =312472004 |Blood calcium measurement (procedure)|}

30%

3

HP:6000554 Positive bloodstream plasmodium falciparum nucleic acid pathogen test.

434156008 |Infectious agent in bloodstream (finding)|:

{363713009 |Has interpretation (attribute)| = 10828004 |Positive (qualifier value)|, 363714003 |Interprets (attribute)| =

(398545005 |Nucleic acid assay (procedure)|:

246093002 |Component (attribute)| =708396002 |Deoxyribonucleic acid of Plasmodium falciparum (substance)|,

370129005 |Measurement method (attribute)|=444077007 |Analysis using reverse transcriptase polymerase chain reaction technique (procedure)|)}

637 (8%)



Links to other pages

Human Phenotype Ontology and SNOMED CT

Clinical examples (2)

HPO to SNOMED mapping

Post-coordinated expressions - the process

Mapping files for download

Next steps -

References


























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