Hi all,

We are looking for feedback related to this LOINC part and associated LOINC terms.

RELMA defines this property as following: “Risk is the probability (chance) of a certain event happening, such as developing a particular disease or inheriting a specific mutation. Risk can be represented as a fraction or a percent. For example, a 1 in 1,000 chance can be represented as 1/1,000 or 0.1%.”

Example LOINC terms that are using this property:

LOINC_NUMLONG_COMMON_NAMECOMPONENTPROPERTYTIME_ASPCTSYSTEMSCALE_TYPMETHOD_TYP
43995-0Trisomy 21 risk [Likelihood] in FetusTrisomy 21 riskLikelihoodPt^FetusQn
49090-4Fetal Trisomy 21 risk [Likelihood] Based on maternal ageTrisomy 21 riskLikelihoodPt^FetusQnBased on maternal age
73970-6Fetal Trisomy 21 risk [Likelihood] based on Plasma cell-free DNA by Dosage of chromosome-specific cfDNATrisomy 21 riskLikelihoodPtPlas.cfDNAQnDosage of chromosome specific cf DNA
75561-1Fetal Trisomy 21 risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNATrisomy 21 riskLikelihoodPtWBC.DNA+Plas.cfDNAQnDosage of chromosome specific cf DNA
75563-7Fetal Trisomy 21 risk [Likelihood] based on Plasma cell-free+WBC DNA by Dosage of chromosome-specific cfDNA NarrativeTrisomy 21 riskLikelihoodPtWBC.DNA+Plas.cfDNANarDosage of chromosome specific cf DNA


For creating post coordinated expression for the examples noted above, our proposal is to:

Create new component concept as following: 
7894007 | Karyotype morphology (morphologic abnormality)
        78989007 | Trisomy (morphologic abnormality)
              NEW | Trisomy 21 (morphologic abnormality)
Create a new property as following
New | Likelihood (property) (qualifier value)

Other attributes (including method) will be mapped as specified in the LOINC terms.

Best Regards,

Farzaneh

CC: Suzanne Santamaria