B.6 Nested Expression Constraints - Invalid Expressions

Expression Constraint	Valid Expression¹
	Precoordinated	Postcoordinated
<< (^ 700043003 \| Example problem list concepts reference set\| )	6143009 \| Diabetic education\|	71388002 \| Procedure\| : 405813007 \| Procedure site - Direct\| = 80891009 \| Heart structure\|
	75367002 \| Blood pressure\|
^ (< 450973005 \| GP/FP health issue reference set\| )	80146002 \| Appendectomy\|	-
	305342007 \| Admission to ward\|
(< 404684003 \|Clinical finding\| : 363698007 \|Finding site\| = << 39057004 \|Pulmonary valve structure\| ) AND ^ 700043003 \|Example problem list concepts reference set\|	125605004 \| Fracture of bone\|	404684003 \| Clinical finding\| : 363698007 \| Finding site\| = 17401000 \| Cardiac valve structure\|
	195967001 \| Asthma\|
(< 404684003 \|Clinical finding\| : 363698007 \|Finding site\| = << 39057004 \|Pulmonary valve structure\| ) AND (< 64572001 \|Disease\| : 116676008 \|Associated morphology\| = << 415582006 \|Stenosis\| )	301104003 \| Pulmonary valve finding\|	404684003 \| Clinical finding\| : 363698007 \| Finding site\| = 39057004 \| Pulmonary valve structure\|
	76107001 \| Spinal stenosis\|	64572001 \| Disease\| : 116676008 \| Associated morphology\| = 415582006 \| Stenosis\|
(<< 17636008 \|Specimen collection\| : 424226004 \|Using device\| = << 19923001 \|Catheter\| ) . 363701004 \|Direct substance\|	57617002 \| Urine specimen collection\|	17636008 \| Specimen collection\| : 424226004 \| Using device\| = 19923001 \| Catheter\|
	122575003 \| Urine specimen\|
(<< 404684003 \|Clinical finding (finding)\| OR << 272379006 \|Event (event)\| ): 255234002 \|After\| = << 71388002 \|Procedure (procedure)\|	293690005 \| Peppermint oil allergy\|	404684003 \| Clinical finding\| : 255234002 \| After\| = 417163006 \| Injury\|
	82510005 \| Posttraumatic vertigo\|
<< 125605004 \|Fracture of bone\| : [0..0] ((<< 410662002 \|Concept model attribute\| MINUS 363698007 \|Finding site\| ) MINUS 16676008 \|Associated morphology\| ) = *	704333004 \| Pathological fracture of hand due to osteoporosis\|	125605004 \| Fracture of bone\| : 42752001 \| Due to\| = 417163006 \| Injury\|
	722571004 \| Linear fracture of skull due to birth trauma\|
< 404684003 \|Clinical finding\| : 47429007 \|Associated with\| = (< 404684003 \|Clinical finding\| : 116676008 \|Associated morphology\| = << 55641003 \|Infarct\| )	3238004 \| Pericarditis\|	64572001 \| Disease\| : 47429007 \| Associated with\| = ( 404684003 \| Clinical finding\| : 363698007 \| Finding site\| = 277712000 \| Cardiac internal structure\| )

Footnotes
Ref	Notes
1	Where necessary, these examples make some assumptions about the membership of the example reference sets.

Expression Constraint	Valid Expression¹
	Precoordinated	Postcoordinated
<< (^ 700043003 \| Example problem list concepts reference set\| )	6143009 \| Diabetic education\|	71388002 \| Procedure\| : 405813007 \| Procedure site - Direct\| = 80891009 \| Heart structure\|
	75367002 \| Blood pressure\|
^ (< 450973005 \| GP/FP health issue reference set\| )	80146002 \| Appendectomy\|	-
	305342007 \| Admission to ward\|
(< 404684003 \|Clinical finding\| : 363698007 \|Finding site\| = << 39057004 \|Pulmonary valve structure\| ) AND ^ 700043003 \|Example problem list concepts reference set\|	125605004 \| Fracture of bone\|	404684003 \| Clinical finding\| : 363698007 \| Finding site\| = 17401000 \| Cardiac valve structure\|
	195967001 \| Asthma\|
(< 404684003 \|Clinical finding\| : 363698007 \|Finding site\| = << 39057004 \|Pulmonary valve structure\| ) AND (< 64572001 \|Disease\| : 116676008 \|Associated morphology\| = << 415582006 \|Stenosis\| )	301104003 \| Pulmonary valve finding\|	404684003 \| Clinical finding\| : 363698007 \| Finding site\| = 39057004 \| Pulmonary valve structure\|
	76107001 \| Spinal stenosis\|	64572001 \| Disease\| : 116676008 \| Associated morphology\| = 415582006 \| Stenosis\|
(<< 17636008 \|Specimen collection\| : 424226004 \|Using device\| = << 19923001 \|Catheter\| ) . 363701004 \|Direct substance\|	57617002 \| Urine specimen collection\|	17636008 \| Specimen collection\| : 424226004 \| Using device\| = 19923001 \| Catheter\|
	122575003 \| Urine specimen\|
(<< 404684003 \|Clinical finding (finding)\| OR << 272379006 \|Event (event)\| ): 255234002 \|After\| = << 71388002 \|Procedure (procedure)\|	293690005 \| Peppermint oil allergy\|	404684003 \| Clinical finding\| : 255234002 \| After\| = 417163006 \| Injury\|
	82510005 \| Posttraumatic vertigo\|
<< 125605004 \|Fracture of bone\| : [0..0] ((<< 410662002 \|Concept model attribute\| MINUS 363698007 \|Finding site\| ) MINUS 16676008 \|Associated morphology\| ) = *	704333004 \| Pathological fracture of hand due to osteoporosis\|	125605004 \| Fracture of bone\| : 42752001 \| Due to\| = 417163006 \| Injury\|
	722571004 \| Linear fracture of skull due to birth trauma\|
< 404684003 \|Clinical finding\| : 47429007 \|Associated with\| = (< 404684003 \|Clinical finding\| : 116676008 \|Associated morphology\| = << 55641003 \|Infarct\| )	3238004 \| Pericarditis\|	64572001 \| Disease\| : 47429007 \| Associated with\| = ( 404684003 \| Clinical finding\| : 363698007 \| Finding site\| = 277712000 \| Cardiac internal structure\| )

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B.6 Nested Expression Constraints - Invalid Expressions