Invalid Refinements

Expression Constraint	INVALID Expression
	Precoordinated	Postcoordinated
< 19829001	disorder of lung	: 116676008	associated morphology	= 79654002	edema	19829001	disorder of lung	19829001	disorder of lung	: 116676008	associated morphology	= 44132006	abscess
	73452002	abscess of lung
		19829001	disorder of lung	: 116676008	associated morphology	= 40829002	acute edema
	233711002	oxygen-induced pulmonary edema
< 19829001	disorder of lung	: 116676008	associated morphology	= << 79654002	edema	19829001	disorder of lung	6141006	retinal edema	: 116676008	associated morphology	= 103619005	inflammatory edema
	73452002	abscess of lung
		19829001	disorder of lung	: 116676008	associated morphology	= 44132006	abscess
	6141006	retinal edema
< 404684003	clinical finding	: 363698007	finding site	= << 39057004	pulmonary valve structure	, 116676008	associated morphology	= << 415582006	stenosis	404684003	clinical finding	448643005	abnormality of pulmonary valve	: 116676008	associated morphology	= = 44132006	abscess
	448643005	abnormality of pulmonary valve
		404684003	clinical finding	: 363698007	finding site	= 61853006	spinal canal structure	, 116676008	associated morphology	= 415582006	stenosis
	431238002	abscess of pulmonary valve
: 246075003	causative agent	= 387517004	paracetamol	46093004	paracetamol measurement	404684003	clinical finding	: 246075003	causative agent	= 372687004	amoxicillin
< 404684003	clinical finding	: { 363698007	finding site	= << 39057004	pulmonary valve structure	, 116676008	associated morphology	= << 415582006	stenosis	}, { 363698007	finding site	= << 53085002	right ventricular structure	, 116676008	associated morphology	= << 56246009	hypertrophy	}	404684003	clinical finding	< 404684003	clinical finding	: { 363698007	finding site	= << 39057004	pulmonary valve structure	, 116676008	associated morphology	= << 56246009	hypertrophy	}, { 363698007	finding site	= << 53085002	right ventricular structure	, 116676008	associated morphology	= << 415582006	stenosis	}
	56786000	pulmonary valve stenosis
< 404684003	clinical finding	: 47429007	associated with	= ( < 404684003	clinical finding	: 116676008	associated morphology	= << 55641003	infarct	)	3238004	pericarditis	64572001	disease	: 47429007	associated with	= (404684003	clinical finding	: 363698007	finding site	= 277712000	cardiac internal structure	)
< 404684003	clinical finding	: << 47429007	associated with	= << 267038008	edema	404684003	clinical finding	95356008	mucosal ulcer	: 42752001	due to	= 59901004	cheek biting
< 111115	amoxicillin tablet	: { 127489000	has active ingredient	= 372687004	amoxicillin	, 111115	has reference basis of strength	= 372687004	amoxicillin	, 111115	strength magnitude equal to	>= #500, 111115	strength unit	= 258684004	mg	} ¹	111115	amoxicillin tablet	111115	amoxicillin tablet	: 111115	has dose form	= 421026006	oral tablet	, { 127489000	has active ingredient	= 372687004	amoxicillin	, 111115	has reference basis of strength	= 372687004	amoxicillin	, 111115	strength magnitude equal to	= #450, 111115	strength unit	= 258684004	mg	}¹⁵
	111115	amoxicillin trihydrate 450 mg tablet	¹⁵
< 111115	amoxicillin tablet	: { 127489000	has active ingredient	= 372687004	amoxicillin	, 111115	has reference basis of strength	= 372687004	amoxicillin	, 111115	strength magnitude equal to	>= #500, 111115	strength magnitude equal to	<= #800, 111115	strength unit	= 258684004	mg	}¹⁵	111115	amoxicillin tablet	111115	amoxicillin tablet	: { 127489000	has active ingredient	= 372687004	amoxicillin	, 111115	has reference basis of strength	= 372687004	amoxicillin	, 111115	strength magnitude equal to	= #820, 111115	strength unit	= 258684004	mg	}¹⁵
	111115	amoxicillin trihydrate 820 mg tablet	¹⁵
< 373873005	pharmaceutical / biologic product	: 111115	trade name	= "PANADOL"¹⁵	373873005	pharmaceutical / biologic product	373873005	pharmaceutical / biologic product	: {127489000	has active ingredient	= 412031009	paracetamol or derivative	}¹⁵
	111115	paracetamol tablet	¹⁵
< 105590001	substance	: R 127489000	has active ingredient	= 111115	TRIPHASIL tablet	¹⁵	105590001	substance	373873005	pharmaceutical / biologic product	: 127489000	has active ingredient	126109000	levonorgestrel	¹⁵
	387517004	paracetamol
< 404684003	clinical finding	: = 79654002	edema	263225007	hip fracture	404684003	clinical finding	: 116676008	associated morphology	= 72704001	fracture
	385933006	edema control education
< 404684003	clinical finding	: 116676008	associated morphology	= *	195967001	asthma	404684003	clinical finding	: 363698007	finding site	= 80891009	heart structure
	73211009	diabetes mellitus	404684003	clinical finding	: 246075003	causative agent	= 372687004	amoxicillin

Footnotes
Ref	Notes
1	Please note that these examples are based on the draft drug concept model available at the time of writing. Concepts for which an identifier has not yet been assigned have been shown with an identifier of '111115'.

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Invalid Refinements