Overview
The dose form transformation represents a process where a dose form is transformed from that supplied by the manufacturer into a new dose form, usually to make it suitable for administration (e.g. dissolving a "powder for solution for injection" dose form into a "solution for injection" dose form). This may occur as part of the dispensing act or immediately before administration. To support fully defining concepts in the 736542009 |Pharmaceutical dose form (dose form)| hierarchy, a hierarchy representing dose form transformation is required.
Concepts in the 736477006 |Dose form transformation (transformation)| hierarchy will be used to model concepts in the 736542009 |Pharmaceutical dose form (dose form)| hierarchy; they will not be used to model concepts in the 763158003 |Medicinal product (product)| hierarchy.
The 736477006 |Dose form transformation (transformation)| hierarchy is a descendant of 362981000 |Qualifier value (qualifier value).
Modeling (stated view)
Descendants shall be modeled as follows.
| Parent concept | <<736477006 |Dose form transformation (transformation)| |
|---|---|
| Semantic tag | (transformation) |
| Definition status | 900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept) |
| Attributes | None |
Naming Guidelines
FSN | Use the following pattern for the FSN where X is the transformation:
Example:
|
|---|---|
Preferred Term | Use the following pattern for the PT where X is the transformation:
Example:
|
Synonyms | Synonyms are not allowed unless explicitly identified as an exception in the Editorial Guidelines. |
| Text Definitions | Preferred; not required. |
Exemplars
The following illustrates the stated and inferred view for 761954006 |No transformation (transformation)|:
The following illustrates the stated and inferred view for 764779004 |Disperse or dissolve (transformation)|:
The following illustrates the stated and inferred view for 736854003 |Disperse (transformation)|:
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