Pharmaceutical Dose Form Naming and Modeling Conventions

736542009 |Pharmaceutical dose form (dose form)

(dose form)

900000000000073002 |Sufficiently defined by necessary conditions definition status (core metadata concept)|

Exceptions:

• • The following concepts cannot be sufficiently defined and will be modeled with the parent concept 736542009 |Pharmaceutical dose form (dose form) and all applicable attributes but will have a Definition status = 900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept); these concepts should classify as leaf nodes in the hierarchy.
    
    • Concepts that reference:
      • coated
      • drug delivery system
      • iontophoresis (e.g. 385113008 |Conventional release solution for iontophoresis (dose form)|)
      • liposomal suspension (e.g. 421943006 |Lyophilized powder for conventional release suspension for injection (dose form)|)
      • nebulizer (e.g. 385198000 |Conventional release solution for nebulizer (dose form)|)
      • particle (421535006 |Gastro-resistant oral particles tablet (dose form)|)
      • pellet (e.g. 420767002 |Gastro-resistant oral pellets capsule (dose form)|)
      • syrup (e.g. 385033009 |Powder for conventional release oral syrup (dose form)|)
      • vapor

Range:  <736479009 |Dose form intended site (intended site) 

Cardinality: 0..*

• • While the allowed range is broader, concepts representing a sufficiently defined pharmaceutical dose form should have one or more |Has dose form intended site| attributes.
    

Exceptions:

• • 785898006 |Conventional release solution for irrigation (dose form)|
    
  • 785910004 |Prolonged-release intralesional implant (dose form)|
    

Range:  <736480007 |Dose form release characteristic (release characteristic) 

Cardinality: 0..1

• • While the allowed range is broader, concepts representing a sufficiently defined pharmaceutical dose form should have one and only one |Has dose form release characteristic| attributes.
    

Range:  <736665006 |Dose form administration method (administration method)

Cardinality: 0..*

• While the allowed range is broader, concepts representing a sufficiently defined pharmaceutical dose form should have one and only one |Has dose form administration method| attributes.

Range:  <736477006|Dose form transformation (transformation)

Cardinality: 0..*

• • While the allowed range is broader, concepts representing a sufficiently defined pharmaceutical dose form should have one and only one |Has dose form transformation| attributes. 

Use the following pattern for the FSN; align naming and case sensitivity with the FSN for the concepts that are selected as the attribute values, excluding the semantic tag. For multiple intended sites, the sites must be in alphabetical order and separated by the word “or”.

• <Dose form release characteristic FSN> <Dose form intended site FSN> <Basic dose form> (dose form)

Example:

• Conventional release oral capsule (dose form)
• Conventional release oral suspension (dose form)
  
• Prolonged-release oral capsule (dose form)
• Conventional release and prolonged-release oral tablet (dose form)
• Conventional release cutaneous cream (dose form)
  
• Conventional release vaginal ointment (dose form)
  
• Gastro-resistant oral suspension (dose form)
  

Use the following pattern for the PT; align naming and case sensitivity with the PT for the concepts that are selected as the attribute values, excluding the semantic tag. For multiple intended sites, the sites must be in alphabetical order and separated by the word “or”. Exclude <Dose form release characteristic> when = 736849007 |Conventional release (release characteristic)|.

• <Dose form release characteristic FSN> <Dose form intended site FSN> <Basic dose form>

Example:

• Oral capsule
• Oral suspension
• Prolonged-release oral capsule
• Conventional release and prolonged-release oral tablet
• Cutaneous cream
• Vaginal ointment
• Gastro-resistant oral suspension

A synonym matching the FSN is required; other synonyms are not allowed unless explicitly identified as an exception in the Editorial Guidelines.

Exceptions:

• Synonyms with eye instead of ocular, ear instead of otic, or nose instead of nasal may be created.