A number of diseases exist in which the literature describes the potential for there to exist a recognised set of associated "systemic manifestations". In an attempt to model these systemic manifestations there has been a requirement to identify a modelling pattern which lies somewhere between the concepts of "Co-occurrent' "Due to".
The issue arose from a discussion on how we should model the systemic manifestation of Sjögren's syndrome and the thread relating to this has been included below as background.