Events, Conditions, Episodes Project Group meeting agenda 09-25-2017

Date

2017-08-28

Team Calendars

See agenda below

Item	Description	Owner	Item	Comments/Files
1	Welcome and role call	BGO, all
2	Allergy/hypersensitivity editorial guidelines	BGO	Update on allergy/hypersensitivity model and allergy to x revision project

Input from Allergy-hypersensitivity clinical reference group
- The term "pseudoallergy" is obsolete as discrete pathophysiologic mechanisms have been identified. Recommendation is to replace with non-allergic hypersensitivity which will align more closely with WAO/EAAAI nomencalture
  |* Yongsheng Gao and Toni Morrison met 8/23/2017 to discuss how to prioritize content revision for Jan. 2018 release.
Yongsheng Gao will produce draft document and will finalize with Bruce Goldberg and Toni Morrison

3	Arthritis syndromes	BGO	Certain arthritis conditions can be represented as a joint inflammation as well as a systemic/multisystem disorder.	Arthropathy systemic disorders.pptx
4	Modeling fetal and maternal related concepts	PBR	Alternate model using occurrence role	fetal_maternal_modelling.pptx
5	Modeling of CVAs due to thrombosis/embolus - follow-up	BGO, PBR	Proposed model was to use specific artery/vein thrombosis concepts as value of due to along with an associated morphology of 78195007	Occlusive thrombus (morphologic abnormality). Issue raised that occlusive thrombus (morphologic abnormality) as residing in role group 0 would refer to theCVA rather than the thrombosis. Suggested solution is to create specific occlusive artery/vein thrombosis concepts as the value of due to

Revised model presented. Same parents inferred as original model. Question of need to revise model as it would require creating many new precoordinated classes
Questions also arose as to the overloading of the morphology hierarchy with structures that increasingly specify a simple morphology by including an underlying cause such as Hemorrhagic infarct (morphologic abnormality)
It was suggested that guidelines need to be developed for when to use a highly specific morphology vs a simple morphology with additional relationships in order to define certain concepts

Question arose as to use cases for developing above guidelines

Queries/data aggregation
|* Stroke_Modelling.docx
|

6

Sepsis/organ dysfunction syndrome

YGA, BGO

Sepsis-associated organ dysfunction (disorder)

. They need to be reviewed and revised following the Editorial Guide on X with Y associations. Some specific issues need to be addressed:

Which pattern should this concept and its subconcepts belong to, e.g. due to vs. co-occurrent and due to?
Should these be implemented as description changes of FSNs or inactivation of concepts?
Should 238151006|Sepsis-associated organ dysfunction (disorder)| be subconcept of 91302008|Sepsis (disorder)|?
Should 91302008|Sepsis (disorder)| is a subconcept of 238149007|Systemic inflammatory response syndrome (disorder)|?
Should sepsis is a subconcept of 238147009|Organ dysfunction syndrome (disorder)|?
Should 76571007|Septic shock (disorder)| is a subconcept of sepsis?|Ongoing discussion has raised the following points:
Organ dysfunction can persist after infection resolves, therefore not necessarily co-occurrent and thus co-occurrent and due to modelling pattern may not be appropriate.
Should sepsis be considered a kind of infectious disease? If so then another model would utilize pathological process infectious process to capture infectious disease as an additional parent.
Is a pathological process of infectious process correct for sepsis or is dysregulated host response a better pathological process to define sepsis?|
7

AOB, adjourn

ALL

Next meeting September 25, 2017 20:00 UTC
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