In the International Release, the | Has active ingredient (attribute)| value should represent the base ingredient, not a modification, unless explicitly identified as an exception below.
| Exceptions | Examples |
| Benzylpenicillin | 1234765004 |Product containing only benzathine benzylpenicillin in parenteral dose form (medicinal product form)| 323404007 |Product containing benzathine benzylpenicillin (medicinal product)| |
Chemical element with multiple modification | 422232005 |Calcium lactate gluconate (substance)| 715220007 |Tenofovir alafenamide (substance)| |
Chloral hydrate | 778711000 |Product containing only chloral hydrate in oral dose form (medicinal product form)| 386735001 |Product containing chloral hydrate in oral dose form (medicinal product form)| 775158004 |Product containing only chloral hydrate (medicinal product)| |
Liposome or lipid complex substances | 426490000 |Vincristine liposome (substance)| 425953004 |Amphotericin B lipid complex (substance)| 768664009 |Amphotericin B phospholipid complex (substance)| 427544000 |Amphotericin B cholesteryl sulfate complex (substance)| |
Pegylated substance | 385544005 |Pegfilgrastim (substance)| 770965008 |Pegvaliase (substance)| |
Radiopharmaceutical | 783865003 |Product containing only cyanocobalamin (58-Co) (medicinal product)| 783867006 |Product containing only cyanocobalamin (58-Co) in oral dose form (medicinal product form)| 783856005 |Product containing sodium iodide (131-I) in parenteral dose form (medicinal product form)| 783854008 |Product containing sodium iodide (131-I) (medicinal product)| |
Silver sulfadiazine | 864009007 |Product containing only silver sulfadiazine in cutaneous dose form (medicinal product form)| 771756000 |Product containing silver sulfadiazine in cutaneous dose form (medicinal product form)| |
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