Overview
The dose form release characteristic represents a general type of pattern of release (e.g. conventional, modified, delayed, prolonged) of the active ingredient substance(s) from the dose form. To support fully defining concepts in the 736542009 |Pharmaceutical dose form (dose form)| hierarchy, a hierarchy representing dose form release characteristics is required.
Concepts in the 736480007 |Dose form release characteristic (release characteristic)| hierarchy will be used to model concepts in the 736542009 |Pharmaceutical dose form (dose form)| hierarchy; they will not be used to model concepts in the 763158003 |Medicinal product (product)| hierarchy.
The 736480007 |Dose form release characteristic (release characteristic)| hierarchy is a descendant of 362981000 |Qualifier value (qualifier value).
Modeling (stated view)
Descendants shall be modeled as follows.
| Parent concept | 736480007 |Dose form release characteristic (release characteristic) or one or more descendants of 736480007 |Dose form release characteristic (release characteristic) |
|---|---|
| Semantic tag | (release characteristic) |
| Definition status | 900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept) |
| Attributes | None |
Naming Guidelines
FSN | Use the following pattern for the FSN where X is the release characteristic, adding a hyphen when appropriate Combined release-characteristic concepts may be created to support modeling of concepts that display multiple release characteristics in a single formulation.
For example,
*Prolonged was selected rather than Extended because feedback was received that it is more clear to translate for non-English speaking users; existing national drug extensions appear to use one or the other of these terms. **Modified-release is a grouper that is not allowed to be used to model a Clinical drug concept. |
|---|---|
Preferred Term | Use the following pattern for the PT where X is the release characteristic, adding a hyphen when appropriate:
For example,
|
Synonyms | Synonyms are not allowed unless explicitly identified as an exception in the Editorial Guidelines. |
| Text Definitions | Preferred; not required. |
Exemplars
The following illustrates the stated and inferred view for 736849007 |Conventional release (release characteristic)|:
The following illustrates the stated and inferred view for 736848004 |Delayed-release (release characteristic)|:
The following illustrates the stated and inferred view for 737594003 |Delayed-release and prolonged-release (release characteristic)|:
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