Introduction

Background

SNOMED CT terminology provides a common language that enables a consistent way of indexing, storing, retrieving, and aggregating clinical data across specialties and sites of care.

SNOMED International maintains the SNOMED CT technical design, the content architecture, the SNOMED CT content (includes the concepts table, the descriptions table, the relationships table, a history table, and ICD mappings), and related technical documentation.

Purpose

This document provides a summarized description of the content changes included in the July 2022 release of SNOMED Clinical Terms^® (SCT) International Release.

It also includes technical notes detailing the known content or technical issues where the root cause is understood, the fix has been discussed and agreed to, but has yet to be implemented.

The SNOMED International Release Notes are available alongside the July 2022 International release.

Scope

This document is written for the purpose described above and is not intended to provide details of the technical specifications for SNOMED CT or encompass every change made during the release.

Audience

The audience includes National Release Centers, WHO-FIC release centers, vendors of electronic health records, terminology developers and managers who wish to have an understanding of changes that have been incorporated into the July 2022 International release.

Please note, you may have to register for a Confluence user account in order to access the links included in these release notes.

Changes to the International Edition Release Schedule

Content Development Activity

Summary

Continuous quality improvement and enhancement of existing content is an ongoing process undertaken by SNOMED International in preparation for every release. The July 2022 International Release has seen a continuation of the work driven by contributions from: Kaiser Permanente i.e. Convergent Medical Terminology (CMT), Global Medical Device Nomenclature Agency (GMDNA), Orphanet and other domain specific collaborations as well as requests received via the Content Request System (CRS). 

Additionally quality improvement activities are advanced via project driven initiatives summarized below.  Additional work items impacting every release are updates to the SNOMED CT derived maps such as ICD-10 and ICD-O; details are included in these release notes.  

Information about editorial decisions may be found in the SNOMED CT Editorial Guide; mapping guidance for ICD-10 can be found here

COVID-19

Content relating to COVID-19 can be viewed here

Any concepts in scope for the SNOMED CT to ICD-10 mapping have been mapped and adhere to the World Health Organization current guidelines.

Updates for Concept Inactivation Values

Please see editorial guidance for changes to concept inactivation values here.

Quality Initiative

The Quality Initiative (QI) project is the implementation of the Quality Strategy. After a successful pilot project for the July 2018 release the next stage has been implemented for subsequent releases including July 2022. 

Quality improvement tasks were deployed to improve internal structural consistency and ensure compliance with editorial policy related to the stated modeling of content. Additionally, correction or addition of defining relationships was carried out to accurately reflect current clinical knowledge and ensure the semantic reliability of descriptions associated with a concept.

Changes made for the Quality Initiative for the July 2022 release are detailed below.

Descriptions update for 128462008 |Secondary malignant neoplastic disease (disorder)| Hierarchy

For consistency of descriptions, 128462008 |Secondary malignant neoplastic disease (disorder)| and its subtypes will have their Fully Specified Name and Preferred Term with 'secondary' changed to 'metastatic' retaining the 'secondary' description as a synonym. The descriptions with 'secondary' will be inactivated and not the concept. Editorial Guidance will be provided.

Complex Flap Procedures

As part of the QI project, work continues to remodel complex flap procedures. This includes some procedures that are subtypes of 234890003 |Repair of cleft palate (procedure)| and also focusing on relevant concepts that are subtypes of 234647001 |Repair of cleft lip (procedure)|. In order to sufficiently define these procedure concepts some improvements have been made to the hierarchy of 87979003 |Cleft palate (disorder)| with the addition of defining relationships. 

Body Structure 

Alveolar Ridge/Process

After consultation with the Dentistry CRG, the terms 'alveolar ridge' and 'alveolar process' are considered synonymous. Body structure concepts have been changed to reflect this. Approximately

9 concepts have been inactivated.

Revision of Male Internal Genital Organ

Revision of 16 concepts related to male internal genital organs.

SEP and Laterality Anatomy Reference Sets

Updated and validated release file for the lateralizable body structure reference set. 

Updated and validated release files for the SEP refsets.

Clinical Finding

Procedure

Has Intent - Diagnostic or Therapeutic

Following completion of the inactivation of endoscopy content stating intent as diagnostic and therapeutic, work has commenced on the inactivation of other concepts with descriptions that refer to the intent of a procedure as diagnostic or therapeutic. The inactivation reason is non-conformance to editorial policy with a historical association of “REPLACED_BY” to an appropriate target replacement concept. The exceptions to this approach would be those procedures that differ in what is actually done depending on whether the intent is diagnostic or therapeutic. This was agreed upon with Member Forum and the Content Managers Advisory Group. This work will take place over several monthly releases beginning with diagnostic procedures.

Organism

Updated terming for descriptions containing Haemophilus influenzae types “a” to “f” such that concepts in other hierarchies are consistent with the terming of associated concepts in the Organism hierarchy, which is the source of truth as specified in the general naming guidelines.

Metadata Concept Inactivation

After consultation, the following metadata concepts have been inactivated for the July 2022 Release:

• 741068007 |SNOMED CT to European Directorate for the Quality of Medicines & HealthCare simple map reference set (foundation metadata concept)|
• 735233007 |European Directorate for the Quality of Medicines & HealthCare simple map reference set module (core metadata concept)|
• 762959004 |European Directorate for the Quality of Medicines & HealthCare to SNOMED CT simple map reference set (foundation metadata concept)|
• 733900009 |SNOMED CT to Unified Code for Units of Measure simple map reference set (foundation metadata concept)|
• 741814003 |SNOMED CT to Unified Code for Units of Measure simple map reference set module (core metadata concept)|

Qualifier Value

Gene Product

6 new qualifier value concepts have been added for gene product metabolizing enzyme activity descriptors.

Substance

Analyte Substance Hierarchy Groupers

Groupers in the Substance hierarchy that refer to analyte (e.g. 259988005 |Transplantation analyte (substance)|, 312273006 |Microbiology analyte (substance)|) have been inactivated with reason Meaning unknown; no potential replacement concept has been provided.

Pharmaceutical/Biological Product

Pharmaceutical/Biological Product

Dose Form Related Changes

Physical Object

Collaboration/Harmonization Agreements

American Joint Committee on Cancer (AJCC) TNM allowable values

Pursuant to an agreement between the American Joint Committee on Cancer and SNOMED International, legacy TNM tumor staging findings originating from outdated editions of the AJCC tumor staging manual have been inactivated.  A complete set of AJCC allowable values for tumor staging representing the current clinical and pathological TNM values as well as tumor stage groups, categories, and grades have been added to SNOMED CT as qualifier values.  These are found under the grouper concept 1222584008 |American Joint Committee on Cancer allowable value (qualifier value)|.  

Convergent Medical Terminology (CMT)

56 new concepts have been added for the July 2022 release predominantly from the domains of ophthalmology, dermatology and respiratory.

Orphanet

Working in collaboration with Orphanet (http://www.orpha.net/consor/cgi-bin/index.php), creation of new concepts for the original set of prioritized rare diseases has been completed. All of the concepts added for the Orphanet project have been mapped to ICD-10.

The Production release of the SNOMED CT to Orphanet Simple Map was published in October 2021. Work is now underway to add further content to the SNOMED CT to Orphanet Simple Map for future releases starting with the next Production release in October 2022.

ICD-11 Update

The July 2022 release has seen continued addition of content for this project.

International Classification for Nursing Practice

13 new nursing procedure concepts have been added.

Cancer Synoptic Reporting

Cancer synoptic reports are used by many member countries to record pathology examination of cancer specimens including the College of American Pathologists (US and Canada), Royal College of Pathology (UK), Royal College of Pathology Australasia (Australia, New Zealand), PALGA (The Netherlands), Swedish Society of Pathology, and others.

For more information about this project, please see Cancer Synoptic Reporting Clinical Project Group 

Internal Quality Improvement

Machine Readable Concept Model (MRCM) Changes

All historical content issues where two or more finding sites were included in a single role group have been resolved in the International release as part of the QI project. There are two MRCM rules for finding site to accommodate the historical content. One MRCM is applicable to all content, it allows more than one finding site in a role group. The other MRCM is only applicable for 'All new precoordinated SNOMED CT content'. The existing MRCM rules have been updated to only allow at most one finding site in a role group from the July 2022 release.

A further change has been made to the MRCM for the July 2022 release:

• MRCM for new attribute 1230370004 |Is vasculature of (attribute)|

Details of changes to the MRCM are here 

SNOMED CT derived products

ICD-10 map

The SNOMED CT to the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (© World Health Organization 1994) 2016 Version map (SNOMED CT to ICD-10 Map) is included in the SNOMED CT International release as a Baseline. The SNOMED CT to ICD-10 Map was created to support the epidemiological, statistical and administrative reporting needs of SNOMED International member countries and WHO Collaborating Centers.

The SNOMED CT to ICD-10 Map is released in Release Format 2 (RF2) only. It is located in the file der2_iisssccRefset_ExtendedMapFull_INT_20200731.txt, which is in the Map folder under Refset, in each of the three RF2 Release Type folders. 

The SNOMED CT to ICD-10 Map is released as Refset 447562003 |ICD-10 complex map reference set (foundation metadata concept)|.

Content development activity summary

The map is a directed set of relationships from SNOMED CT source concepts to ICD-10 target classification codes.  The SNOMED CT source domains for the MAP are limited to subtypes of 404684003 |clinical finding|, 272379006 |event| and 243796009 |situation with explicit context|.  The target classification codes are ICD-10 2016 release. 

Mapped content for July 2022

The map provided for the July 2022 release has been updated, and now represents a complete map from SNOMED CT International release to ICD-10 2016 version.

• 197 newly authored concepts have been added and mapped.

• The SNOMED to ICD-O (morphology) map has 2 additional concept added as a result of the ICD-O 3.2 review or added due to CRS requests.

We would welcome feedback on any issues that users of the map may detect when using the map. Issues should be submitted via mapping@snomed.org

Technical Guide Exemplars

The Technical Guide Exemplars document has now been moved from the International Edition release package to a Confluence page.  This page can be found as part of the ICD-10 Mapping Technical Guide (see Appendix B), which is hosted here:  http://snomed.org/icd10map

SNOMED CT to OWL conversion and classification

The repository containing the toolkit enabling simple SNOMED CT to OWL conversion and classification can be found here, including documentation on its use: https://github.com/IHTSDO/snomed-owl-toolkit

Please contact SNOMED International at support@snomed.org if you would like to provide any feedback on ways to extend and improve the new toolkit.

Technical notes

Known Issues

Known Issues are content or technical issues where the root cause is understood, and the resolution has been discussed and agreed but has yet to be implemented.  This can be due to a number of reasons, from lack of time within the new monthly editing cycles, to the risk of impact to the stability of SNOMED CT if the fix were to be deployed at that stage in the Product lifecycle.  

For the current SNOMED CT International edition, the following Known Issues were identified, and agreed to be resolved in future editing cycles:

Resolved Issues

Resolved issues are Known Issues which were not fixed as part of the previous release lifecycle, but which have now been resolved in the latest release.  They can also be issues found during testing of the current release, which were resolved before the final deployment of the Production release.  Finally they can be issues which were reported or found during the testing phase, but which have been closed without any action taken.  

The Resolved Issues for the current SNOMED CT International edition can be found here:

Technical updates

RF2 package format

For future reference, the RF2 package convention dictates that it contains all relevant files, regardless of whether or not there is content to be included in each particular release.  Therefore, the package contains a mixture of files which contain both header rows and content data, and also files that are intentionally left blank (including only a header record).  The reason that these files are not removed from the package is to draw a clear distinction between files that:

• have been deprecated (and therefore removed from the package completely), due to the content no longer being relevant to RF2 in this or future releases, and 

• happen to contain no data in this particular release (and are therefore included in the package but left blank, with only a header record), but are still relevant to RF2, and could therefore potentially contain data in future releases.

This allows users to easily distinguish between files that have purposefully been removed or not, as otherwise if files in option 2 above were left out of the package it could be interpreted as an error, rather than an intentional lack of content in that release.

Configuration file in the RF2 package, containing Release Metadata 

A new file has been included since the July 2020 International Edition, containing metadata about the Release package itself.  This has been created in conjunction with feedback from the community, and as such initially contains the following fields:

• effectiveTime
  

• previouslyPublishedPackage

• languageRefset(s)

• licenceStatement

The file is in .JSON format, to ensure that it is both machine-readable and human-readable, and is named "release_package_information.json".

The metadata will be extended and refined going forward, in order to ensure that it contains the most useful information possible. If you have any ideas about any other useful information to include, please send them to info@snomed.org, along with a business case explaining how the information would benefit stakeholders.  Please be aware that this use case will then be assessed by SNOMED International, and the new metadata will only be included in the configuration file if the business case is strong enough.  

New Association References

In order to support the Content changes above in section 2.3, the following Association Reference set members have been added to the International Edition from the April 2022 release onwards:

• 1186921001|POSSIBLY REPLACED BY association reference set
  
• 1186924009|PARTIALLY EQUIVALENT TO association reference set

Early visibility of impending changes in the upcoming 2022 Monthly International Edition releases

Please see the following page for details of all upcoming changes planned for 2022: 

•  https://confluence.ihtsdotools.org/display/RMT/2022+Early+Visibility+Release+Notice+-+Planned+changes+to+upcoming+SNOMED+International+Release+packages