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Overview

The Medicinal |Product " containing " (MP-containing) concept is an abstract representation x (medicinal product)| concepts are abstract representations of the active ingredient(s) for a medicinal product. It means that the The medicinal product must contain the active ingredient(s) specified in the FSN but may also contain a modification of the active ingredient(s) specified in the FSN or may contain additional active ingredient(s).

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• • Product containing axitinib (medicinal product)
  • Product containing abacavir and lamivudine (medicinal product) 

Modeling

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Stated parent

concept

	763158003 |Medicinal product (product)
Semantic tag	(medicinal product)
Definition status

900000000000073002 |Sufficiently defined by necessary conditions definition status (core metadata concept)|

Defined
Attribute: Has active ingredient	Range: <105590001 |Substance (substance) excluding concepts representing structural groupers, dispositions, or combined substances Cardinality: 1..*  There is no technical limit on the number of Has active ingredient attributes that may be added to a concept; a practical limit may be imposed at a later date

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For content in the International Release, this attribute value should represent the base ingredient, not a modification, unless explicitly identified as an exception.

Exceptions:

Chemical element with multiple modification (e.g. 422232005 |Calcium lactate gluconate (substance)|)

Chloral hydrate (e.g. 28748001 |Product containing chloral hydrate (medicinal product)|)

Liposome or lipid complex substances (e

.

g. 426490000 |Vincristine liposome (substance)|, 425953004 |Amphotericin B lipid complex (substance)|)

Pegylated substance (e.g. 385544005 |Pegfilgrastim (substance)|, 770965008 |Pegvaliase (substance)|)

Radiopharmaceutical (e.g. 783864004 |Product containing cyanocobalamin (58-Co) (medicinal product)|, 783854008 |Product containing sodium iodide (131-I) (medicinal product)|)

Silver sulfadiazine (e.g. 19630009 |Product containing silver sulfadiazine (medicinal product)|)

Benzylpenicillin (e.g. 323404007 |Product containing benzathine benzylpenicillin (medicinal product)|)

Naming

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FSN

Use the following pattern for the FSN

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and PT.  Align naming and case sensitivity with the FSN for the concept that is selected as the attribute value

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For multiple ingredient drug products, the active ingredients must be in alphabetical order and separated by the word “and”.

FSN

Product containing <Active ingredient FSN> (medicinal product) Product containing <Active ingredient FSN> and <Active ingredient FSN> (medicinal product) Product containing <Active ingredient FSN> and <Active ingredient FSN> and <Active ingredient FSN tag> (medicinal product) For example, Product containing axitinib (medicinal product) Product containing abacavir and lamivudine (medicinal product) Product containing abacavir and lamivudine and zidovudine (medicinal product)

Preferred Term

Use the following pattern for the PT; align naming and case sensitivity with the PT for the concept that is selected as the attribute value.

For multiple ingredient drug products, the active ingredients must be in alphabetical order and separated by the word “and”.

	<Active ingredient PT>-containing product <Active ingredient PT>- and <Active ingredient PT>-containing product <Active ingredient PT>- and <Active ingredient PT>- and <Active ingredient PT>-containing product For example, Axitinib-containing product Abacavir- and lamivudine-containing product Abacavir- and lamivudine- and zidovudine-containing product
Synonym	Synonyms matching the FSN are not required.

Exemplars

The following illustrates the stated view for 714627007 |Product containing aflibercept (medicinal product)|:

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