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Representation of radioactive isotopes

Modeling

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Parent concept	Most distal appropriate descendant of 89457008 |Radioactive isotope (substance)|

Exceptions: none

Most distal appropriate descendant of 33638001 |Isotope (substance)|

• Exceptions: none

Exceptions: none

Semantic tag	(substance)
Definition status

900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept)|

Primitive
Attribute:

Is

Modification738774007 | Is

modification of	Range  <105590001 |Substance (substance)| Cardinality: 0..*

Exceptions: none identified

One relationship to be created to represent each modified component of the substance
Attribute:

Has disposition	Range:  <726711005 |Disposition (disposition)| NOTE: While the allowed range is broader, substance concepts should only use descendants of the concept 726711005 |Disposition (disposition)| as the attribute value. Cardinality: 0..1

Exceptions: none identified

Naming

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Superscripts should should not be used in either Fully Specified Name, Preferred Term, or Synonymssynonyms.

FSN	Pattern: [name of isotope]-[atomic number] (substance)

Example:

For example, Gallium-67 (substance)
Preferred Term	Pattern: [name of isotope]-[atomic number]

Example:

For example, Gallium-67
Synonyms	Pattern: [atomic number]-[chemical symbol]

Example:

For example, 67-Ga

No synonyms should exist using the superscript notation.

Exemplar

The following illustrates the hierarchy view:

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Representation of radioisotope with salt

Modeling

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Parent concept	Most distal appropriate descendant of 89457008 |Radioactive isotope (substance)|

Exceptions: noneExceptions: none

Semantic tag	(substance)
Definition status

900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept)|

Primitive
Attribute:

Is modification

738774007 | Is modification

of	Range  <105590001 |Substance (substance)| Cardinality: 0..*

Exceptions: none identified

One relationship to be created to represent each modified component of the substance
Attribute:

Has disposition	Range:  <726711005 |Disposition (disposition) | NOTE: While the allowed range is broader, substance concepts should only use

descendants of the concept 726711005

<726711005 |Disposition (disposition)| as the attribute value. Cardinality: 0..1

Exceptions: none identified

Naming

...

Superscripts should should not be used in either Fully Specified Name, Preferred Term, or Synonymssynonyms.

Parentheses should be used to delineate the atomic number and chemical symbol from the rest of the terming, ; this aligns with INN.  

FSN	Pattern:

[name of isotope] ([atomic number]-[chemical symbol]) [salt] (substance)

Example:

For example, Gallium (67-Ga) citrate (substance)
Preferred Term	Pattern:

[name of isotope] ([atomic number]-[chemical symbol]) [salt]

Example:

For example, Gallium (67-Ga) citrate

Synonyms

Pattern:

• none identified

Exemplar - radioisotope with salt

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Representation of combined radioisotope substances

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Modeling 

Naming

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Superscripts should should not be used in either Fully Specified Name, Preferred Term, or Synonymssynonyms.

The Fully Specified Name should explicitly state that a component was “labeled” by a radioisotope in the FSN. Do not use “with”, “and”, or “tagged”.  

Omit the word “labeled” from the PT, ; keep a synonym to match the FSN.  

Exemplar - combined radioisotope substances

The following illustrates both the stated and inferred view:

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