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Cancer Synoptic Reporting Project Group

9-January-2023 at 15:30 - 16:30 UTC

Discussion items

ItemDescriptionOwnerNotesAction
1Record meetingScott Campbell 



 Cannot do!  Not a host Done!!

2Closing gaps in content - dysplasia and neoplasia at marginsScott Campbell 
  1. Need references

  2. Questions:
    1. When is a #plasia generalized vs. localized (i.e., by organ)



  1. Definitions of high-grade/low-grade glandular dysplasia
  2. Definitions of high-grade/low-grade glandular intraepithelial neoplasia
  3. Definitions of high-grade/low-grade squamous intraepithelial neoplasia
  4. Sample of observable entity concepts created

Observable entity concepts are fine.  Jim Case asked for documentation on the *plasias and High-/Low- grading definitions as supporting documentation for ongoing use

Scott Campbell will draft a "blurb" and pathologists on the call will provide appropriate citations.


1/9/2023 - HG dysplasia vs. CIS.

Discussed the use of HG dysplasia, carcinoma in situ (CIS), and the and/or version.  This needs to be reviewed as the and/or for lymphovascular invasion body structure does not look correct for subsumption and classification.  GCIs may not be possible as they need defining attributes.

RE: #plasias.  Thomas Ruediger  supports a single set of morphologic abnormality concepts for glandular dysplasia, glandular intraepithelial neoplasia, squamous dysplasia, intraepithelial squamous neoplasia that are completely organ agnostic.

@ stefandubois suggests that such a conflation of concepts will require a comprehensive review by organ system.

In my opinion, both are correct.  This dovetails nicely into the Histology QI project.

The CSRWG needs to address what needs to/can be done to get the synoptic reporting content deliverable in the shorter term while also addressing the longer term Histology QI issue.

3Missing body structures
  1. Async?  Out of sync (wink)

Not discussedScott Campbell will put lists of concepts needed together for group review via email.  Discussions can happen asynchronously
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4Wilms tumor/nephroblastoma NICTIZ
  1. requests from Elze de Groot

Scott Campbell to follow up.  Paul Seegers forwarded protocolSIOP-F4.pdf

Scott Campbell meeting with Nictiz on Friday, 1/16/23

5GU histologies
  1. Looking for interested parties

@stefan dubois; @brian rous; @ross simpson will assist.  Scott Campbell will get meetings started.

6Follow up on protocol review by authoritative bodiesScott Campbell 
  1. Documents of SNOMED CT terminology binding across major protocol producers

Scott Campbell will forward marked up ICCR, RCPath protocols to team for review of SNOMED CT content bindings.

  1. ICCR
  2. CAP

Needs to be followed up in another meeting.

8Business meeting
  1. In person/mixed
2 > half days; Also pathology CRG will meet f2f


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