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Bounded reference sets are designed to be used together with a specific information model. For example, if a reference set is developed as a value set for recording the smoking status in a specific software system, like shown in the example illustrated below.

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When a reference set is bound to a specific information model, it is important to carefully consider how the binding affect the reference set members. So, for bounded reference sets it is important to clearly specify the relationship between the reference set and the associated information model to guide users, and to ensure correct interpretation of data, when data is subsequently retrieved for purposes such as display, analytics and communication. 

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For unbounded reference sets it is important for consistent and proper use to clearly specify the purpose and use of the reference set. Therefore, written specification and guidelines should be developed and distributed together with the reference set, to ensure that users of the reference set know how to implement and use the reference set.

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