46866001 |Fracture of lower limb|

12611008 |Bone structure of tibia|

72704001 |Fracture|

92196005 |Benign neoplasm of lung| 

39607008 |Lung structure|

3898006 |Neoplasm, benign| 

92038006 |Benign neoplasm of bronchus|

955009 |Bronchial structure|

3898006 |Neoplasm, benign|

60667009 |Closed fracture of rib| 

113197003 |Bone structure of rib|

34305007 |Fracture, multiple, closed| 

36991002 |Closed fracture of upper limb|

371195002 |Bone structure of upper limb|

16119006 |Abscess of jaw|

70925003 |Bone structure of maxilla|

44132006 |Abscess|

109327001 |Abscess of facial bone|

128234004 |Disorder of maxilla|

Using input data shown in  to populate the given expression template will result in following four expressions.

	=== 46866001 |Fracture of lower limb|:
		{ 363698007 |Finding site| = 12611008 |Bone structure of tibia|,
		  116676008 |Associated morphology |= 72704001 |Fracture| }

	<<< 92196005 |Benign neoplasm of lung| + 92038006 |Benign neoplasm of bronchus|:
		{ 363698007 |Finding site| = 39607008 |Lung structure|,
		  116676008 |Associated morphology| = 3898006 |Neoplasm, benign| },
		{ 363698007 |Finding site| = 955009 |Bronchial structure|,
		  116676008 |Associated morphology| = 3898006 |Neoplasm, benign| }

	<<< 60667009 |Closed fracture of rib| + 
	36991002 |Closed fracture of upper limb| :
		{ 363698007 |Finding site| = 113197003 |Bone structure of rib|,
		  363698007 |Finding site| = 371195002 |Bone structure of upper limb|,
		  116676008 |Associated morphology| = 34305007 |Fracture, multiple, closed|}

	=== 16119006 |Abscess of jaw| + 
		109327001 |Abscess of facial bone| +
		128234004 |Disorder of maxilla|:
			{ 363698007 |Finding site| = 70925003 |Bone structure of maxilla|, 
			  116676008 |Associated morphology| = 44132006 |Abscess|}

Example 2

The expression template below is used as a pattern for family history expressions. It contains a nested relationship group (i.e. SSgroup) inside the outer relationship group (i.e. AFgroup). To populate this expression template, the input data must be clear as to where each value should be used, and how these values should be grouped into relationship groups and expressions.

	[[+id (<< 413350009 |Finding with explicit context| ) @Condition]]:
		[[ 1..2 @AFgroup ]] { [[1..1]]  246090004 |Associated finding|  = ([[+id (<<  404684003 |Clinical finding| ) @Finding]]:
			[[0..1 @SSgroup]] { [[0..1]]  246112005 |Severity|  = [[+id (<  272141005 |Severities| ) @Severity]],
								[[0..1]]  363698007 |Finding site|  = [[+id (<  91723000 |Anatomical structure| ) @Site]] }),
						[[1..1]]  408732007 |Subject relationship context|  = [[+id (<  444148008 |Person in family of subject| ) @Relationship]],
						[[1..1]]  408731000 |Temporal context|   = [[+id (<  410510008 |Temporal context value| ) @Time]],
						[[1..1]]  408729009 |Finding context|   = [[+id (<  410514004 |Finding context value| ) @Context]] }

To support the creation of input data for this expression template, the logical model in  above can be specialized as shown below in . Please note that this model has been simplified by removing unnamed logical classes, which have a cardinality of 1..1 and no data attribute. 

This logical model can be populated with input data, as shown below in .

266898002 |Family history: Respiratory disease|

195967001 |Asthma|

24484000 |Severe|

444301002 |Mother of subject|

410589000|All times past|

410515003 |Known present|

161077003 |Father smokes|

77176002 |Smoker|

255604002 | Mild|

444295003 |Father of subject|

15240007 |Current|

410515003 |Known present|

161078008 |Mother smokes|

77176002 |Smoker|

24484000 |Severe|

444301002 |Mother of subject|

15240007 |Current|

410515003 |Known present|

160288009 |Family history: neoplasm of skin| 

372130007 |Malignant neoplasm of skin|

6736007 |Moderate|

113179006 |Skin structure of nose|

444304005 |Sister of subject|

410511007 |Current or past (actual)|

410515003 |Known present|

275937001 |Family history of cancer|

255604002 |Mild|

88089004 |Skin structure of lip|

Using the input data shown above to process the given expression template will result in following three expressions.

	266898002 |Family history: Respiratory disease|:
		{ 246090004 |Associated finding| = (195967001 |Asthma|: { 246112005 |Severity| = 24484000 |Severe| }),
		   408732007 |Subject relationship context| = 444301002 |Mother of subject|,
		   408731000 |Temporal context| = 410511007 |Current or past (actual)|,
		   408729009 |Finding context| = 410515003 |Known present| }

	161077003 |Father smokes| + 161078008 |Mother smokes|:
		{ 246090004 |Associated finding| = (77176002 |Smoker|: { 246112005 |Severity| = 24484000 |Severe| }),
		   408732007 |Subject relationship context| = 444295003 |Father of subject|,
		   408731000 |Temporal context| = 15240007 |Current|,
		   408729009 |Finding context| = 410515003 |Known present|},
		{ 246090004 |Associated finding| = (77176002 |Smoker|: { 246112005 |Severity| = 255604002 |Mild| }),
		   408732007 |Subject relationship context| = 444301002 |Mother of subject|,
		   408731000 |Temporal context| = 15240007 |Current|,
		   408729009 |Finding context| = 410515003 |Known present| }

	160288009 |Family history: neoplasm of skin| + 275937001 |Family history of cancer|:
		{ 246090004 |Associated finding| = (372130007 |Malignant neoplasm of skin|:
				{ 246112005 |Severity| = 6736007 |Moderate|, 363698007 |Finding site| = 113179006 |Skin structure of nose| },
				{ 246112005 |Severity| = 255604002 |Mild|, 363698007 |Finding site| = 88089004 |Skin structure of lip| }), 
		408732007 |Subject relationship context| = 444304005 | Sister of subject|,
		408731000 |Temporal context| = 410511007 |Current or past (actual)|,
		408729009 |Finding context| = 410515003 |Known present| }

Example 3

The expression template below represents a procedure with a single method and one or more procedure devices. Please note that in the first attribute name-value pair, both the attribute name and the attribute value use a slot. Because this name-value pair is repeatable, the input data needs to include an attribute name-value pair slot to ensure that the corresponding attribute name and attribute value stays connected.

	[[+id (<< 71388002 |Procedure|) @Procedure]]:
		[[1..1 @Group]]
			{ [[1..* @PD_ANVpair]] [[+id (< 405815000 |Procedure device|) @DeviceType]] = [[+ (<260787004 |Physical object|) @Device]],
			  [[1..1]] 260686004 |Method| = [[+ (<129264002 |Action (qualifier value)|) @Method]] }

To support the creation of input data for this expression template, the logical model in  above can be specialized as shown below in . Please note that this model has been simplified by removing unnamed logical classes, which have a cardinality of 1..1 and no data attribute. 

This logical model can be populated with input data, as shown below in . Please note that because the first attribute name-value pair is repeatable and uses a replacement slot for both the attribute name and attribute value, the input data needs to include the attribute name-value pair slot to ensure that the corresponding attribute name and attribute value stays connected.

387713003 
|Surgical procedure|

363699004 
|Direct device|

2282003 
|Breast prosthesis, device|

257867005 
|Insertion - action|

71388002 
|Procedure|

363699004 
|Direct device|

313025003 
|Hearing aid battery|

282089006 
|Replacement - action|

363710007
|Indirect device|

6012004
|Hearing aid, device|

Using the input data shown in  to process the given expression template will result in the following two expressions.

	387713003 |Surgical procedure|:
            { 363699004 |Direct device| = 2282003 |Breast prosthesis, device|,
              260686004 |Method| = 257867005 |Insertion - action|}

	384728007 |Replacement of device|:
            { 363699004 |Direct device| = 313025003 |Hearing aid battery|,
              363710007 |Indirect device| = 6012004 |Hearing aid, device|,
              260686004 |Method| = 282089006 |Replacement - action|}

Example 4

The expression template below represents a 

	64572001 |Disease|: 
		[[@Group]] { 363698007 |Finding site|  =  [[+ (<< 272673000 |Bone structure|) @Site]],
					 116676008 |Associated morphology|  =  [[+ (<< 72704001 |Fracture|) @Morphology]] }

To support the creation of input data for this expression template, the logical model in  above can be specialized as shown below in . Please note that this model has been simplified by removing unnamed logical classes, which have a cardinality of 1..1 and no data attribute. 

Image Modified

 below shows some example input data for the above template represented using the tabular format used in the previous examples.

In addition to this tabular representation, there are a wide variety of other possible formats for representing template input data, including json, xml, tsv, csv etc. The exact format used will depend on the format required by the template processor. For example, the above input data can be represented in JSON as shown below.

{"Expression Data": [
        { "Group": [
                {  "Site":"312763008 |Bone structure of trunk|",
                    "Morphology":"72704001 |Fracture|" },
                {  "Site": "84667006 |Bone structure of cervical vertebra|",
                    "Morphology": "72704001 |Fracture|" } ] },
        { "Group": [
                {  "Site":"71341001 |Bone structure of femur|",
                    "Morphology": "72704001 |Fracture|" } ] },
        { "Group":[  
                {  "Site":"12611008 | Bone structure of tibia|",
                    "Morphology": "72704001 |Fracture|" } ] } ] }

Simplification of Data Representation