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Bound substances Overview

Creation of substance concepts that contain “bound” is limited to the measurement of biological substances (Observable entities, evaluation procedures, LOINC collaboration project) or to report their level (clinical findings).

Concepts are modeled with an Is modification of (attribute) relationship to the corresponding unspecified substance. Where the substance is "bound" the molecule to which the substance is bound to may be specified in the term.

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Modeling

Parent concept

Most distal appropriate descendant of 115668003 |Biological substance (substance)|

Semantic tag

(substance)

Definition status

900000000000074008 |Necessary but not sufficient concept definition status (core metadata concept)|Primitive

Attribute

738774007 |Is modification of (attribute)|

726542003 |Has disposition (attribute)|

Terming Guidelines

FSN

Pattern: Bound X (substance)

For example,

      • Bound insulin (substance)
      • Protein bound iodine (substance)
      • Albumin bound thyroxine (substance)

Preferred Term

Pattern: Bound X (substance)

For example,

      • Bound insulin
      • Protein bound iodine (substance)
      • Albumin bound thyroxine (substance)

Exemplar

The following illustrates the stated view:

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