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Stated parent concept

The stated parent concept must be the concept that represents the structural grouper. If such a concept does not exist, it must be created and its stated substance descendants added before the grouper based on both structure and disposition can be created.

  • Exceptions: none

Definition status

900000000000073002 |Sufficiently defined concept definition status (core metadata concept)

  • Exceptions: none

Attribute:

Has disposition

  • Range:  726711005 <726711005 |Disposition (disposition) - descendants only
    • NOTE: While the allowed range is broader, the Substance Groupers based on both Structure and Disposition should only use descendants of the concept 726711005 |Disposition (disposition) as the attribute value.
    Exceptions: none identified
  • Cardinality: 1..1
  • Exceptions: none identified

Exemplar for Grouper Concept Based on both Structure and Disposition

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FSN

Use the following pattern for the FSN, with X representing the structure and Y representing the disposition. The FSN should align with the FSN for the substance grouper and disposition used as the stated parent and attribute value respectively.

  • X with Y mechanism of action (substance)
Example:

For example,

      • Piperazine derivative with histamine H1 receptor antagonist mechanism of action (substance)
      • Substance with dihydropyridine derivative structure and calcium channel blocker mechanism of action (substance)
      • Substance with organophosphorus structure and acetylcholinesterase inhibitor mechanism of action (substance)

Preferred Term

Use the following pattern for the Preferred Term, with X representing the structure and Y representing the disposition. The FSN should align with the FSN for the substance grouper and disposition used as the stated parent and attribute value respectively.

  • X Y
Example:

For example,

      • Piperazine derivative histamine H1 receptor antagonist
      • Dihydropyridine derivative calcium channel blocker
      • Organophosphorus acetylcholinesterase inhibitor

Synonyms

A synonym to match the FSN is not required.

Additional synonyms are allowed only if they are consistent with the synonyms for the corresponding structure grouper and disposition.

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