Page History

763158003 |Medicinal product (product)

Range: 105590001 |Substance (substance) - descendants only, excluding concepts representing structural groupers, dispositions, or roles

Cardinality: 1..* - there

There is no technical limit on the number of Has active ingredient attributes that may be added to a concept; a practical limit may be imposed at a later date.

For content in the International Release, this attribute value should represent the base ingredient, not a modification, unless explicitly identified as an exception.

• Exceptions:
  
  • Chemical element with multiple modification (e.g. 422232005 |Calcium lactate gluconate (substance)|)
  • Chloral hydrate (e.g. 386735001 |Product containing chloral hydrate in oral dose form (medicinal product form)|)
  • Liposome or lipid complex substances(e.g. 426490000 |Vincristine liposome (substance)|, 425953004 |Amphotericin B lipid complex (substance)|, 768664009 |Amphotericin B phospholipid complex (substance)|, 427544000 |Amphotericin B cholesteryl sulfate complex (substance)|)
  • Pegylated substance (e.g. 385544005 |Pegfilgrastim (substance)|, 770965008 |Pegvaliase (substance)|)
  • Radiopharmaceutical (e.g. 783866002 |Product containing cyanocobalamin (58-Co) in oral dose form (medicinal product form)|, 783856005 |Product containing sodium iodide (131-I) in parenteral dose form (medicinal product form)|)
  • Silver sulfadiazine (e.g. 771756000 |Product containing silver sulfadiazine in cutaneous dose form (medicinal product form)|)
  • Benzylpenicillin (e.g. 713760005 |Product containing benzathine benzylpenicillin in parenteral dose form (medicinal product form)|)

Range: 736542009 |Pharmaceutical dose form (dose form) - descendants that are groupers representing intended site only (e.g. 385268001 |Oral dose form (dose form)|, 385287007 |Parenteral dose form (dose form)|)

Cardinality: 1..1

Exceptions: 

• 385217004 |Conventional release gas for inhalation (dose form)| may be used as manufactured dose form for Medicinal product form concepts.
• 785898006 |Conventional release solution for irrigation (dose form)| does not have 736474004 |Has dose form intended site (attribute)| but can be used as a target for manufactured dose form for Medicinal product form concepts.