Page History

The proposal seems generally reasonable.

A few value sets in NLM's Value Set Authority Center refer to Allergy to animal x dander (finding) concepts and will be directly affected if we do inactivation/creation rather than modification (which I can understand for editorial reasons).

I am wondering whether procedure concepts also referring to "animal x dander" remain appropriate or would need to be refactored similarly to the corresponding Allergy concepts – they could be similarly genericized (e.g., Cat allergen  specific immunoglobulin E antibody measurement). Just a thought.

• https://www.thermofisher.com/phadia/wo/en/product-catalog.html?articleNumber=14-4109-01&region=AU
• https://www.thermofisher.com/phadia/wo/en/product-catalog.html?articleNumber=14-5240-01&region=AU
• https://www.thermofisher.com/phadia/wo/en/product-catalog.html?articleNumber=14-4905-01&region=AU

There are also tests for urine, serum, epithelium individually and combinations of

• https://www.thermofisher.com/phadia/wo/en/product-catalog.html?articleNumber=14-4326-01&region=AU

Otherwise, I think the change is reasonable for Clinical Findings. It's consistent to how 232350006|House dust mite allergy| is modelled.

Presumably, this doesn't just apply to dander but all the 'animal materials', ie. feathers.
Will this logic/pattern apply to reactions also? i.e. <<418448002|Allergic reaction caused by animal (disorder)| (although there's limited content here at the moment).

Will this pattern also be extended to plants? pollens/seed

Could just use even general substances like 'dog material substance' (Subtsance from dog)

Are the FSN and PT in the example correct?

In the example if the PT is | Allergy to horse | the FSN would be | Allergy to horse protein |, but can you talk about at ‘horse protein’? This sounds especially strange if this statement in the Summary is true: “In addition, the same allergenic protein may be found in several different sources”. I suppose this means that the same allergenic protein can be found in e.g. a zebra and so it would not be a ‘horse protein’ only.

I am thinking that maybe the FSN should have been | Allergy to Animal protein x |, but this would not match the PT | Allergy to horse | either.

I am not an allergist, but a terminologist, so perhaps I just do not understand this subject. Perhaps an example with an actual case would be helpful? /Camilla