September 12, 2019 agenda Allergy CRG meeting

Bruce Goldberg

Bruce Goldberg, Natasha Krul

Create general animal groupers with accompanying PT which reflects the accepted clinical idioms.

• Ensure that the 'allergy substance (protein)' exists and include the animal insulin derived allergy substances within this hierarchy.
• CRG group members to propose detailed content required (see below*)
• Submit via CRS and prioritise appropriately and/or as part of Bruce Goldberg's work in the allergy group.

• Allergy to animals.pptx
• *We (Natasha Krul )have a very active allergist in an academic hospital who has provided us with a list of relevant allergens. He has divided the list into categories like inhalation allergens, food allergens etc. and for each group of allergens he would like a 'header'  for instance 'pulse vegetables' as a header for peas, peanuts, beans etc so the allergist who is registering the information can choose what level he wants to register in. I understand there a plans to create a 'header' in Snomed for animal feathers, protein, dander, epithelium? Am I correct?

Bruce Goldberg, Marie-Alexandra Lambot

• Continuing work by Marie-Alexandra Lambot on creating an allergen and allergy refset for use in Belgium

• Other_allergyto_to create_SIG20190906.xlsx
• AnimalSubstances_SIG20190906.xlsx
• Pollens_allergyto_to create_SIG20190906.xlsx
• Foods_allergyto_to create_SIG20190906.xlsx
• Drugs_allergyto_to create_SIG20190906.xlsx

Bruce Goldberg, Natasha Krul

• Cytotoxic and cytostatic often used interchangeably in clinical literature although can be differentiated based on studies in scientific literature
• Individual drugs may exhibit both properties possibly related to dose and other factors
• List of drugs that would be classified as cytotoxic vs. cytostatic is missing
• Requires use case

• Natasha Krul awaiting reply from her hospital pharmacologist to see if she knows of any medication that falls into one of the two categories. 
  • "The reason we came to this question was during our translation project. We saw synonyms in Snomed (cytotoxic and cytostatic) of which we werent sure if they were real synonyms and whether or not we should add them to our translations. I have asked several pharmacologists including a pharmacologist specialised in oncylytic medication and they all said that currently no distinction is made between cytotoxic and cytostatic. It depends on the dose whether a substance is toxic or static". 

Bruce Goldberg, ALL

• Begin group review

• Task completed in SCA. Under review

• https://authoring.ihtsdotools.org/#/tasks/task/INTQA/INTQA-2587/edit

Bruce Goldberg, All